Protein Alignment Pten and Ptprd

DIOPT Version :9

• Sequence 1: NP_001162933.1
• Gene: Pten / 43991
• FlyBaseID: FBgn0026379
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: XP_036019731.1
• Gene: Ptprd / 19266
• MGIID: 97812
• Length: 1966
• Species: Mus musculus
• Alignment Length: 370
• Identity: 72/370 - (19%)
• Similarity: 125/370 - (33%)
• Gaps: 135/370 - (36%)

  Fly    73 YKIYNLCSERSYDVAKFRGRVAVYP---FDDHNPPTIELIQRF--CSDVDMWLKEDSSNVVAVHC 132
            :.:|...|....:|.:|  :...:|   ..:|..|.:..::|.  |:..|       :..:.|||
Mouse  1552 FALYKNGSSEKREVRQF--QFTAWPDHGVPEHPTPFLAFLRRVKTCNPPD-------AGPMVVHC 1607

  Fly   133 KAGKGRTGTMICAYLVFSGIK--KSAD------------------------------EA------ 159
            .||.||||..|....:...||  |:.|                              ||
Mouse  1608 SAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNT 1672

  Fly   160 ------LAWYDEKRTKDRKGVTIPSQ----RRYVQ---YFSKLVCSSVPYSKVSLNVCEIRFSES 211
                  |..|.:|.|:...|..:...    :|...   :.|:.:.:::|.:|....:..|...||
Mouse  1673 EVPARNLYAYIQKLTQIETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYES 1737

  Fly   212 S--CVQNLGMVECSISVLHDSATENAKPDRLKTLPID---FQKSFVLTIKPSIPVSGD------- 264
            :  |:|.:..||.|              |.:....:|   .||:::.|..|....:.|
Mouse  1738 TRVCLQPIRGVEGS--------------DYINASFLDGYRQQKAYIATQGPLAETTEDFWRMLWE 1788

  Fly   265 ----VKFELTK-KSPDKIICH-FW--------------------LNTFFVRNYSPCES-DG---T 299
                :...||| :...:..|| :|                    :..:.:|.:...:: ||   |
Mouse  1789 HNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRT 1853

  Fly   300 VNKYIHT------LSKSE------IDDVHKDSEHKRFSEEFKISI 332
            |.::..|      :.||.      |..|||..|  :|.::..||:
Mouse  1854 VRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKE--QFGQDGPISV 1896

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pten	NP_001162933.1	PTPc	58..167	CDD:304379	28/142 (20%)
		PTEN_C2	196..335	CDD:287393	38/191 (20%)
Ptprd	XP_036019731.1	I-set	31..123	CDD:400151
		Ig strand A'	39..43	CDD:409353
		Ig strand B	46..55	CDD:409353
		Ig strand C	61..66	CDD:409353
		Ig strand C'	69..72	CDD:409353
		Ig strand D	75..83	CDD:409353
		Ig strand E	84..94	CDD:409353
		Ig strand F	102..110	CDD:409353
		Ig strand G	113..123	CDD:409353
		IgI_2_RPTP_IIa_LAR_like	135..234	CDD:409400
		Ig strand B	151..155	CDD:409400
		Ig strand C	164..168	CDD:409400
		Ig strand E	198..202	CDD:409400
		Ig strand F	212..217	CDD:409400
		Ig strand G	224..227	CDD:409400
		IgI_3_RPTP_IIa_LAR_like	247..328	CDD:409401
		Ig strand B	261..265	CDD:409401
		Ig strand C	274..278	CDD:409401
		Ig strand E	295..299	CDD:409401
		Ig strand F	307..312	CDD:409401
		Ig strand G	320..323	CDD:409401
		FN3	331..420	CDD:238020
		FN3	427..519	CDD:238020
		FN3	524..612	CDD:238020
		FN3	620..714	CDD:238020
		FN3	721..827	CDD:238020
		FN3	832..927	CDD:238020
		FN3	930..1021	CDD:238020
		FN3	1031..>1092	CDD:238020
		R-PTPc-D-1	1388..1671	CDD:350472	26/127 (20%)
		R-PTP-D-2	1672..1963	CDD:350476	46/241 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910