DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pten and K07F5.8

DIOPT Version :9

Sequence 1:NP_001162933.1 Gene:Pten / 43991 FlyBaseID:FBgn0026379 Length:514 Species:Drosophila melanogaster
Sequence 2:NP_501766.1 Gene:K07F5.8 / 177833 WormBaseID:WBGene00010636 Length:284 Species:Caenorhabditis elegans


Alignment Length:250 Identity:48/250 - (19%)
Similarity:95/250 - (38%) Gaps:77/250 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 TISLMSNVIRNVVSKKRIRYKEKGYDLDLTYINDNIIAMGYPAPDKLEGL-FRNRLEDVFKLLEE 67
            ||.::.|            |||||......|:         |..|..:.: |:.:.:.|....|.
 Worm    85 TIFMLCN------------YKEKGAKKCHEYL---------PTEDNKDTMSFKEKGQKVTVKFES 128

  Fly    68 NHAQHYKIYNLCSERSYDVAKFRG------RVAVY---PFDDHNPPT-----IELIQRFCSDVDM 118
            :.|..:: .|..::.:..|....|      :|..|   .:.|...||     :||:::       
 Worm   129 SKAIKFR-DNSAAKVTKTVLTVEGAGCDKLKVNHYHWIDWPDRGVPTADNAILELLEK------- 185

  Fly   119 WLKEDSSNVVAVHCKAGKGRTGTMICA-----YLVFSGIKKSADEALAWYDEKRTKDRKGVTIPS 178
              ...|...:||||.||.||||:::..     .|:...|.:..|:.:     ::.::::..::.:
 Worm   186 --ARVSKGPIAVHCSAGIGRTGSVVMLEYVMDQLLAGQIIEDTDKII-----QKIREQRNNSVQT 243

  Fly   179 QRRYVQYFSKLVCSSVPYSKVSLNVCEIRFSESSCVQNLGMVECSISVLHDSATE 233
            ..:|:.           ..:|.:|..|.|          |:::.:.|.:|...|:
 Worm   244 DHQYLF-----------VHQVMMNFFEKR----------GLLDEATSAIHKDFTD 277

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PtenNP_001162933.1 PTPc 58..167 CDD:304379 27/127 (21%)
PTEN_C2 196..335 CDD:287393 8/37 (22%)
K07F5.8NP_501766.1 Y_phosphatase 19..256 CDD:278528 41/217 (19%)
PTPc 20..256 CDD:238006 41/217 (19%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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