Protein Alignment Pten and F54C8.4

DIOPT Version :9

• Sequence 1: NP_001162933.1
• Gene: Pten / 43991
• FlyBaseID: FBgn0026379
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_001254988.1
• Gene: F54C8.4 / 176323
• WormBaseID: WBGene00010037
• Length: 359
• Species: Caenorhabditis elegans
• Alignment Length: 404
• Identity: 74/404 - (18%)
• Similarity: 126/404 - (31%)
• Gaps: 155/404 - (38%)

  Fly    12 IRNVVSKKR-IRYKEKGYDLDLTYINDNIIAMGYPAPDKLEGLFRNRLEDVFKLLEENHAQHYKI 75
            :.||:.:.| |.:|        |.||..:       ..|:....|....|:|:.|.|.......:
 Worm    18 VGNVIPRTRFIVFK--------TPINSQL-------STKIHKEQRFTTNDLFRQLSERGQYLGLV 67

  Fly    76 YNLC-SERSYDVAKFRGRVAVY-----------PFDDHNPPTIELIQRFCSDVDMWLKEDSSNVV 128
            .:|. ::|.||.....|....|           ..||......::||.:....|     |...::
 Worm    68 VDLSDTDRYYDKKDITGMCVQYEKVNCPGRGFIERDDCVESFHQVIQDYTDKCD-----DPDALI 127

  Fly   129 AVHCKAGKGRTGTMICAYLVFSGIKKSADEALAWYDE----------------KRTKDRKGVTIP 177
            .|||..|..|.|.:||.:|: ..:..|:.||:..:::                |..||::...:.
 Worm   128 GVHCTNGINRCGYLICRFLI-DRLGWSSHEAIDAFEQARGYSIEKGAYVMALHKAAKDKRDKQVD 191

  Fly   178 S----------------QRRYVQYFSKLVCSSVPYSKVSLNVCEIRFSESSCVQNLGMVECSISV 226
            |                .|..|::.:.::.:::                   :..||....|:|
 Worm   192 SDSDSSERQRKKKNKRKHREIVEHENIVLINTI-------------------IGELGSQAASVS- 236

  Fly   227 LHDSATENAKPDRLKTLPIDFQKSFVLTIKPSIPVSGDVKFELTKKSPDKIICHFWLNTFFVR-- 289
                             ..|:|.|      |: .||.|         |.:...|.|  .|.::
 Worm   237 -----------------GTDYQNS------PN-GVSVD---------PGQPQPHHW--GFAIKRS 266

  Fly   290 -------------NYSPCESDGTVNKYIHTLSKSEIDDVHKDSEHKRFSEEFKISIVFEAENFSN 341
                         |..|..|:||                  ..|.:.|.|:|: .|..|.|....
 Worm   267 KYAQLNQPVANGANTPPEPSEGT------------------PQEEEEFEEDFE-EIEEETETEPG 312

  Fly   342 DVQAEASEKERNEN 355
            ..|:.:|::....|
 Worm   313 KGQSVSSKRRARRN 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pten	NP_001162933.1	PTPc	58..167	CDD:304379	28/136 (21%)
		PTEN_C2	196..335	CDD:287393	25/153 (16%)
F54C8.4	NP_001254988.1	PTPc	<66..166	CDD:304379	24/105 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910