Protein Alignment Pten and gak

DIOPT Version :9

• Sequence 1: NP_001162933.1
• Gene: Pten / 43991
• FlyBaseID: FBgn0026379
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: XP_009299488.1
• Gene: gak / 100151158
• ZFINID: ZDB-GENE-041210-358
• Length: 1280
• Species: Danio rerio
• Alignment Length: 605
• Identity: 142/605 - (23%)
• Similarity: 240/605 - (39%)
• Gaps: 155/605 - (25%)

  Fly     1 MANTISLMSNVIRNVVSKKRIRYKEKGYDLDLTYINDNIIAMGYPAPDKLEGLFRNRLEDVFKLL 65
            :.|.....|.||::|.|..    ..|| ||||:||...:..|.:|| :.:|...:|.:|||...|
Zfish   380 LTNIKDTSSKVIQSVASSS----YAKG-DLDLSYITSRLAVMSFPA-EGVESAIKNNIEDVRLFL 438

  Fly    66 EENHAQHYKIYNLCSERSYDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDSSNVVAV 130
            :..||.||.:||| |:|||..|:|..||:...:.....||::.:...|.::..|||:|..|:..|
Zfish   439 DSRHAGHYAVYNL-SKRSYRPARFHNRVSECGWQPRRAPTLKNLYSICKNMHQWLKQDQRNICIV 502

  Fly   131 HCKAGKGRTGTMICAYLVFSGIKKSADEALAWYDEKRTKDRKGVTIPSQRRYVQYFSKLVCSS-- 193
            ||..|:..:..::||:|.|..:..:|:.|:..:..||..  .|:: .|.:||::|...::...
Zfish   503 HCLDGRAASAVVVCAFLCFCRLFSTAEAAVYMFSMKRCP--PGIS-ASHKRYIEYMCDMMAEEPI 564

  Fly   194 VPYSKVSLNVCEIRFSESSCVQNLGMVE--------------CSISVLHDS-ATENAKPDRLKTL 243
            :|:||            ...::::.|..              |.:.|..:. ||.:.:.||::..
Zfish   565 IPHSK------------PITIRSVAMTPVPLFNKQRNGCRPFCEVYVGDERVATTSQEYDRMRDF 617

  Fly   244 PIDFQKSFVLTIKPSIPVSGDVKF-----------ELTKKSPDKIICHFWLNTFFV-RNYSPCES 296
            .::..::   .|..:|.|.|||..           .|..|.....:.....:|.|| ||.|
Zfish   618 KMEDGRA---EIPLNITVQGDVLIVIYHARSTLGGRLQAKMASMKMFQIQFHTGFVPRNAS---- 675

  Fly   297 DGTVNKYIHTLSKSEID--DVHKDSEHKRFSEEFKISIVFEA-------------ENF------- 339
              ||.     .:|.::|  |:     .:::.:.|::.:..|.             |||
Zfish   676 --TVK-----FAKYDLDACDI-----QEKYPDLFQVHVNVEVEPQDRPSNKTPPWENFATKGLNP 728

  Fly   340 -----SNDVQAE--------------------ASEKERNENVLNFERSDYDSLSPNCYAEKKVLT 379
                 |.|.|.|                    ||:..::||..:..:::.||.||.
Zfish   729 KILFSSRDEQQEILTKFGKPELPRQPGSTACYASDPPQSENSPDDPQTESDSPSPQ--------- 784

  Fly   380 AIVNDNTTKSQTIETL---------DHKDIVTKIQYDTSTNSKNTSTACKRKQPNSKTLLPSLND 435
               :.:|..:...:||         ||.|.....|.|.|..|:..|.:      .|..:..:|:.
Zfish   785 ---STDTNANNFFQTLDWEDTSRHFDHADGHLDDQEDLSGGSEEESVS------YSAPIEGTLSR 840

  Fly   436 STKEEIKRNHIFNQPSIKKTDL--IKWQNSE---VHITSDTRSINENKNINYNSYITCKQSSPKF 495
            .|.|.:......|.|...:.|.  :...|||   ....|..:|...|.|: .|..:...|::...
Zfish   841 DTSEPLFEADFTNTPPEAQPDTEDLLGLNSEPGPAVPESGLKSSASNSNL-LNDLLFAPQTNTVP 904

  Fly   496 NCGTED--GEEDWESGESTY 513
            :...||  ||   ::||..:
Zfish   905 SASNEDLMGE---DAGEDLF 921

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pten	NP_001162933.1	PTPc	58..167	CDD:304379	37/108 (34%)
		PTEN_C2	196..335	CDD:287393	29/167 (17%)
gak	XP_009299488.1	STKc_GAK	39..320	CDD:270938
		S_TKc	41..311	CDD:214567
		PTEN_C2	566..704	CDD:287393	30/168 (18%)
		DnaJ	<1228..1273	CDD:99751

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910