DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pten and yeats2

DIOPT Version :9

Sequence 1:	NP_001162933.1	Gene:	Pten / 43991	FlyBaseID:	FBgn0026379	Length:	514	Species:	Drosophila melanogaster
Sequence 2:	XP_012825478.1	Gene:	yeats2 / 100135359	XenbaseID:	XB-GENE-5865259	Length:	1238	Species:	Xenopus tropicalis

Alignment Length:	226	Identity:	49/226 - (21%)
Similarity:	88/226 - (38%)	Gaps:	44/226 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   311 EIDDVHKDSEHK------RFSEEFKISIVFEAENFSNDVQAEASEKERNENVLNFER-------- 361
            :|..||::..||      |.:...||..:.: |.|..:::.:..|.|..:..||..|
Frog    17 DISVVHQNKRHKAAETTARDATILKIESIIK-EQFVTELKNKEHEVEVIDQRLNEARRMMDKLRA 80

  Fly   362 -------------------SDYDSLSPNCYAEKKVLTAIVNDNTTKSQTIETLDHKDIVTKIQY- 406
                               |.||:...|..:.||.|.:....::..:|..||....:..|...|
Frog    81 CIVANYYASAALNKNQEGPSSYDATVLNHPSIKKFLESPSRASSPANQRSETPSVANSETDSVYT 145

  Fly   407 -----DTSTNSKNTSTACKRKQPNSKTLL-PSLNDSTKEEIKRNHIFNQPSIKKTDLIKWQNSEV 465
                 |.|.::|..: |.|..:|...|:. ||:|::|:.::.|.....:..:|||.::  .|...
Frog   146 HNEDKDGSLDAKGPA-ANKALRPEGNTVKDPSINENTERQVSRTEDGPRRFVKKTIVV--GNVSK 207

  Fly   466 HITSDTRSINENKNINYNSYITCKQSSPKFN 496
            :|..|.|..|:.....:..|:...:..|..:
Frog   208 YIPPDKREENDQSTHKWMVYVRGSRKEPSID 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pten	NP_001162933.1	PTPc	58..167	CDD:304379
Pten	NP_001162933.1	PTEN_C2	196..335	CDD:287393	8/29 (28%)
yeats2	XP_012825478.1	YEATS	221..300	CDD:281374	2/18 (11%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2283
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900