Protein Alignment Sep5 and SEPTIN7

DIOPT Version :9

• Sequence 1: NP_651961.1
• Gene: Sep5 / 43990
• FlyBaseID: FBgn0026361
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: XP_011513958.1
• Gene: SEPTIN7 / 989
• HGNCID: 1717
• Length: 460
• Species: Homo sapiens
• Alignment Length: 410
• Identity: 160/410 - (39%)
• Similarity: 250/410 - (60%)
• Gaps: 35/410 - (8%)

  Fly     7 EKKTQEVATKVPRLLQLGGHVGFDTLPDQLVNKSVQNGFSFNILCIGETALGKSTLMDTLFNTSF 71
            |:::...:|.|.:...|.|:|||..||:|:..|||:.||.|.::.:||:.||||||:::||.|..
Human    11 EERSVNSSTMVAQQKNLEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDL 75

  Fly    72 GST--PSP-HNL-PNVKLKANTYELQESNVRLKLTVCDTIGYGDQVNKADSYKALVEYVDSQFEA 132
            .|.  |.| |.: ..|:::.:...::|..|:|.||:.||.|:||.|:.::.::.:::|:||:||.
Human    76 YSPEYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFED 140

  Fly   133 YLQEELKIQRAMASAHDGRVHACLYFICPTGHGLKAMDLVCMKQLDTRVNIIPVIAKADTISKSE 197
            ||..|.::.|....  |.||..|||||.|:|||||.:|:..||:|..:|||||:||||||::..|
Human   141 YLNAESRVNRRQMP--DNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEE 203

  Fly   198 LSGFKERIMDELRRNNVSIYQFP-MDDETVSETNAAMNGHLPFAVVGSTEFVKVAGKQVRARQYP 261
            ...||::||.|::.:.:.||:|| .|||..::....:...||.|||||...::|.||:||.||||
Human   204 CQQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIKDRLPLAVVGSNTIIEVNGKRVRGRQYP 268

  Fly   262 WGAVHIENEAHCDFVKLREMLIRTNMEDLREQTHTRHYELFRQRRLQQMGFVDVDSN-------- 318
            ||...:||..||||..||.|||||:|:||::.|:..|||.:|.|:|..:.:..||:|
Human   269 WGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNNKNKGQLTK 333

  Fly   319 ----------NQPVSFQQTFESKRSDHLACLQAKEEEVRQMFVQRVKQKENELKDNEKELHTKFD 373
                      ..|::   ..|.:|.:|:|.::..|.|:.|:|..:||:|..:|||:|.|
Human   334 HLMITLNIRDRSPLA---QMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAE------ 389

  Fly   374 RLKREHLEEKAQLEEARRQL 393
             ::|..|..:..|::.|.::
Human   390 -VQRTFLASEKGLQKKRHRV 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sep5	NP_651961.1	CDC3	25..394	CDD:227352	156/392 (40%)
		CDC_Septin	43..311	CDD:206649	122/272 (45%)
		BAR	<252..405	CDD:299863	57/160 (36%)
SEPTIN7	XP_011513958.1	CDC3	29..419	CDD:227352	156/392 (40%)
		CDC_Septin	47..317	CDD:206649	122/271 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5019
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D845354at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820