Protein Alignment Septin5 and SHS1

DIOPT Version :10

• Sequence 1: NP_651961.1
• Gene: Septin5 / 43990
• FlyBaseID: FBgn0026361
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_010056.1
• Gene: SHS1 / 851373
• SGDID: S000002384
• Length: 551
• Species: Saccharomyces cerevisiae
• Alignment Length: 497
• Identity: 126/497 - (25%)
• Similarity: 216/497 - (43%)
• Gaps: 125/497 - (25%)

  Fly    39 KSVQNGFSFNILCIGETALGKSTLMDTLFNT-------SFG-STPSPHNLPNVKLKANT------ 89
            |..:.|.::.:|..|....||:...:.|..|       .:| |..|..:.|.||:.|.|
Yeast    16 KEHKRGITYTMLLCGPAGTGKTAFANNLLETKIFPHKYQYGKSNASISSNPEVKVIAPTKVVSFN 80

  Fly    90 -----------YELQESNVRLKLTVC--------------------DTI--------GYGDQVNK 115
                       ::...:|:...:|:.                    ||:        |.|:.::.
Yeast    81 SKNGIPSYVSEFDPMRANLEPGITITSTSLELGGNKDQGKPEMNEDDTVFFNLIMTHGIGENLDD 145

  Fly   116 ADSYKALVEYVDSQFEAYLQEELKIQRAMASAHDGRVHACLYFICPTGHGLKAMDLVCMKQLDTR 180
            :...:.::.|::.||:..|.||.:|:| .....|.|||..||||.||||||:.:|:..||.:...
Yeast   146 SLCSEEVMSYLEQQFDIVLAEETRIKR-NPRFEDTRVHVALYFIEPTGHGLREVDVELMKSISKY 209

  Fly   181 VNIIPVIAKADTISKSELSGFKERIMDELRRNNVSIYQF---PMDDETVS-ETNAAMNGHLPFAV 241
            .|::|:|.:||:.:|.||:.|::.||.::.|.||.||:|   |.||:..| |.|.|:....|||:
Yeast   210 TNVLPIITRADSFTKEELTQFRKNIMFDVERYNVPIYKFEVDPEDDDLESMEENQALASLQPFAI 274

  Fly   242 VGSTEFVKVAGKQVRARQYPWGAVHIENEAHCDFVKLREMLIRTNMEDLREQTHTRHYELFRQRR 306
            : :::.....|:.|  |:||||.:.|:::...|...|:.:|..:::::.::.|....||.:|..:
Yeast   275 I-TSDTRDSEGRYV--REYPWGIISIDDDKISDLKVLKNVLFGSHLQEFKDTTQNLLYENYRSEK 336

  Fly   307 L------QQMG---------------FVDVDSNNQPVSFQQTFESKRSD---HLACLQAKEEE-- 345
            |      :::|               |..:.|..|..|.|....:.|:|   :......||.|
Yeast   337 LSSVANAEEIGPNSTKRQSNAPSLSNFASLISTGQFNSSQTLANNLRADTPRNQVSGNFKENEYE 401

  Fly   346 ----------------VRQMFVQRVKQKENELKDNEKELHTKFDRLKREHLEEKAQLEE------ 388
                            |||:..:..::.||.::..:.|...||  |....|.|:.:|..
Yeast   402 DNGEHDSAENEQEMSPVRQLGREIKQENENLIRSIKTESSPKF--LNSPDLPERTKLRNISETVP 464

  Fly   389 ---------ARRQ-LEE----DCQELQRRRLQMANGSHTLTL 416
                     ||:| |||    ..:|||:|..::...:|.|.|
Yeast   465 YVLRHERILARQQKLEELEAQSAKELQKRIQELERKAHELKL 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Septin5	NP_651961.1	CDC_Septin	43..311	CDD:206649	89/330 (27%)
		COG4913	<274..>416	CDD:443941	43/203 (21%)
SHS1	NP_010056.1	CDC3	1..519	CDD:227352	126/497 (25%)