DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sep5 and Septin9

DIOPT Version :9

Sequence 1:	NP_651961.1	Gene:	Sep5 / 43990	FlyBaseID:	FBgn0026361	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	XP_038942878.1	Gene:	Septin9 / 83788	RGDID:	708523	Length:	583	Species:	Rattus norvegicus

Alignment Length:	295	Identity:	120/295 - (40%)
Similarity:	191/295 - (64%)	Gaps:	14/295 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 GHVGFDTLPDQLVNKSVQNGFSFNILCIGETALGKSTLMDTLFNTSFGSTP----SPHNLP-NVK 84
            |:||.|::.:|:..|:::.||.|||:.:|::.||||||::|||.:......    |...:| .::
  Rat   275 GYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPISEERIPKTIE 339

  Fly    85 LKANTYELQESNVRLKLTVCDTIGYGDQVNKADSYKALVEYVDSQFEAYLQEELKIQRAMASAHD 149
            :|:.|::::|..||:||||.||.|:||.:|..:.::.::::::.|:|.|||||:.|.| .....|
  Rat   340 IKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVNINR-KKRIPD 403

  Fly   150 GRVHACLYFICPTGHGLKAMDLVCMKQLDTRVNIIPVIAKADTISKSELSGFKERIMDELRRNNV 214
            .|||.|||||..|||.|:.:|:..||:|...|||:||||||||::..|...||:||..:|..|.:
  Rat   404 TRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERVYFKQRITSDLLSNGI 468

  Fly   215 SIY---QFPMD--DETVSETNAAMNGHLPFAVVGSTEFVKVAGKQVRARQYPWGAVHIENEAHCD 274
            .:|   :|..|  |..|:|....|   :|||||||....:|.||::..|:..||.:.:||..||:
  Rat   469 DVYPQKEFDEDAEDRLVNEKFREM---IPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCE 530

  Fly   275 FVKLREMLIRTNMEDLREQTHTRHYELFRQRRLQQ 309
            |..||::||||:|:::::.|...|:|.:|.:||.:
  Rat   531 FAYLRDLLIRTHMQNIKDITSNIHFEAYRVKRLNE 565

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sep5	NP_651961.1	CDC3	25..394	CDD:227352	120/295 (41%)
		CDC_Septin	43..311	CDD:206649	114/277 (41%)
		BAR	<252..405	CDD:299863	23/58 (40%)
Septin9	XP_038942878.1	PHA03247	<38..232	CDD:223021
Septin9	XP_038942878.1	CDC_Septin	293..567	CDD:206649	114/277 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D845354at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920