Protein Alignment Sep5 and SEPTIN3

DIOPT Version :9

• Sequence 1: NP_651961.1
• Gene: Sep5 / 43990
• FlyBaseID: FBgn0026361
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_001350774.1
• Gene: SEPTIN3 / 55964
• HGNCID: 10750
• Length: 856
• Species: Homo sapiens
• Alignment Length: 321
• Identity: 135/321 - (42%)
• Similarity: 200/321 - (62%)
• Gaps: 11/321 - (3%)

  Fly     1 MVHLVTEKKTQEVATKVPRLL--QLGGHVGFDTLPDQLVNKSVQNGFSFNILCIGETALGKSTLM 63
            |..||.|.:.:......|..:  .|.|::|.||:.:|:..|:::.||.|||:.:|::.||||||:
Human   512 MSELVPEPRPKPAVPMKPMSINSNLLGYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLV 576

  Fly    64 DTLFNTSFGSTPSPHN----LP-NVKLKANTYELQESNVRLKLTVCDTIGYGDQVNKADSYKALV 123
            :|||.:......|..|    :| .|::||..:.::|..|::||||.||.|:|||:|..:.::.:.
Human   577 NTLFKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPIE 641

  Fly   124 EYVDSQFEAYLQEELKIQRAMASAHDGRVHACLYFICPTGHGLKAMDLVCMKQLDTRVNIIPVIA 188
            :|::.|:|.:|:||:.|.| .....|.|||.|||||.||||.|:.:||..||.|...||||||||
Human   642 KYINEQYEKFLKEEVNIAR-KKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNIIPVIA 705

  Fly   189 KADTISKSELSGFKERIMDELRRNNVSIY---QFPMDDETVSETNAAMNGHLPFAVVGSTEFVKV 250
            ||||::..|.|.||:|:..||..|.:..|   :|..|.|..:|.:......:|||||||.:..:|
Human   706 KADTMTLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFAVVGSDKEYQV 770

  Fly   251 AGKQVRARQYPWGAVHIENEAHCDFVKLREMLIRTNMEDLREQTHTRHYELFRQRRLQQMG 311
            .||:|..|:.|||.:.:||..||:|..||:.:|||:::||:|.||..|||.:|.:||...|
Human   771 NGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYETYRAKRLNDNG 831

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sep5	NP_651961.1	CDC3	25..394	CDD:227352	129/295 (44%)
		CDC_Septin	43..311	CDD:206649	122/275 (44%)
		BAR	<252..405	CDD:299863	29/60 (48%)
SEPTIN3	NP_001350774.1	CDC_Septin	557..831	CDD:206649	122/274 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5019
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51948
OrthoDB	1	1.010	-	-		D845354at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.830