Protein Alignment Septin5 and SEPTIN4

DIOPT Version :10

• Sequence 1: NP_651961.1
• Gene: Septin5 / 43990
• FlyBaseID: FBgn0026361
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_001355700.1
• Gene: SEPTIN4 / 5414
• HGNCID: 9165
• Length: 996
• Species: Homo sapiens
• Alignment Length: 362
• Identity: 142/362 - (39%)
• Similarity: 216/362 - (59%)
• Gaps: 31/362 - (8%)

  Fly    26 HVGFDTLPDQLVNKSVQNGFSFNILCIGETALGKSTLMDTLFNTS-------FGSTPSPHNLPNV 83
            :|||.|||:|:..|||:.||.|.::..||:.||||||:::||.|.       .|:  ....:..|
Human   642 YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGA--EERIMQTV 704

  Fly    84 KLKANTYELQESNVRLKLTVCDTIGYGDQVNKADSYKALVEYVDSQFEAYLQEELKIQRAMASAH 148
            ::..:..:::|..|||:||:.||.|:||.||..:.:|.:.||:|.|||.|.::|..:.|  .:..
Human   705 EITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNR--KNIQ 767

  Fly   149 DGRVHACLYFICPTGHGLKAMDLVCMKQLDTRVNIIPVIAKADTISKSELSGFKERIMDELRRNN 213
            |.|||.|||||.|.||||:.:|:..||.|..||||:|::|||||::..|:...|.:|.:|:....
Human   768 DNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFG 832

  Fly   214 VSIYQFP----MDDETVSETNAAMNGHLPFAVVGSTEFVKVAGKQVRARQYPWGAVHIENEAHCD 274
            :.|||||    .:||.....:.|:...:||||:||...|:..|::||.|.||||.|.:||..|||
Human   833 IKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCD 897

  Fly   275 FVKLREMLIRTNMEDLREQTHTRHYELFRQRRLQQMGFVDVDSNNQ-----------PVSFQQTF 328
            |||||.||:||:|:||::.|...|||.:|.:.:|.|..:.|...|:           |:......
Human   898 FVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVPPG 962

  Fly   329 ESKRSDHLACLQAKEEEVRQMFVQRVKQK-ENELKDN 364
            ....::.|  ::.|:||:|:|  |.:..| :.::|:|
Human   963 TDPETEKL--IREKDEELRRM--QEMLHKIQKQMKEN 995

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Septin5	NP_651961.1	CDC_Septin	43..311	CDD:206649	118/278 (42%)
		COG4913	<274..>416	CDD:443941	33/103 (32%)
SEPTIN4	NP_001355700.1	DUF4655	10..534	CDD:434779
		Septin	660..932	CDD:395596	117/275 (43%)