Protein Alignment Sep5 and SEPTIN5

DIOPT Version :9

• Sequence 1: NP_651961.1
• Gene: Sep5 / 43990
• FlyBaseID: FBgn0026361
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_002679.2
• Gene: SEPTIN5 / 5413
• HGNCID: 9164
• Length: 369
• Species: Homo sapiens
• Alignment Length: 369
• Identity: 148/369 - (40%)
• Similarity: 221/369 - (59%)
• Gaps: 29/369 - (7%)

  Fly     4 LVTEKKTQEVATKVPRLLQLGGHVGFDTLPDQLVNKSVQNGFSFNILCIGETALGKSTLMDTLFN 68
            |.|.:..|::..:         :|||.|||:|:..|||:.||.|.::..||:.||||||:.:||.
Human    11 LATPEDKQDIDKQ---------YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFL 66

  Fly    69 TSFGS-----TPSPHNLPNVKLKANTYELQESNVRLKLTVCDTIGYGDQVNKADSYKALVEYVDS 128
            |....     :........|::..:|.:::|..|:||||:.||.|:||.||..:.:|.:.:|||.
Human    67 TDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQ 131

  Fly   129 QFEAYLQEELKIQRAMASAHDGRVHACLYFICPTGHGLKAMDLVCMKQLDTRVNIIPVIAKADTI 193
            |||.|.::|..:.|  .:..|.|||.|||||.|.||||:.:|:..||.|..:|||:|:|||||.:
Human   132 QFEQYFRDESGLNR--KNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCL 194

  Fly   194 SKSELSGFKERIMDELRRNNVSIYQFPM----DDETVSETNAAMNGHLPFAVVGSTEFVKVAGKQ 254
            ..||:...||||.:|:.:..:.:||||.    :||...:.:..:....||||:||...|:..|::
Human   195 VPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQR 259

  Fly   255 VRARQYPWGAVHIENEAHCDFVKLREMLIRTNMEDLREQTHTRHYELFRQRRLQQM-GFVDVDSN 318
            ||.|.||||.|.:||:|||||||||.|||||:|.||::.|...|||.:|...:||| ..:..||.
Human   260 VRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTSKLTQDSR 324

  Fly   319 NQ---PVSFQQTFESKRSDHLACLQAKEEEVRQM--FVQRVKQK 357
            .:   |:....|.:::..   ..::.|:||:|:|  .:||:||:
Human   325 MESPIPILPLPTPDAETE---KLIRMKDEELRRMQEMLQRMKQQ 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sep5	NP_651961.1	CDC3	25..394	CDD:227352	145/348 (42%)
		CDC_Septin	43..311	CDD:206649	122/277 (44%)
		BAR	<252..405	CDD:299863	49/112 (44%)
SEPTIN5	NP_002679.2	Septin	42..313	CDD:395596	119/272 (44%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	51..58		4/6 (67%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	108..111		2/2 (100%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	189..192		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5019
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D845354at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820