Protein Alignment Septin5 and SEPTIN2

DIOPT Version :10

• Sequence 1: NP_651961.1
• Gene: Septin5 / 43990
• FlyBaseID: FBgn0026361
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: XP_024308688.1
• Gene: SEPTIN2 / 4735
• HGNCID: 7729
• Length: 428
• Species: Homo sapiens
• Alignment Length: 362
• Identity: 149/362 - (41%)
• Similarity: 217/362 - (59%)
• Gaps: 33/362 - (9%)

  Fly     7 EKKTQEVATKVPRLLQLGGHVGFDTLPDQLVNKSVQNGFSFNILCIGETALGKSTLMDTLFNTSF 71
            ::.||.:..:.|      |:|||..||:|:..|||:.||.|.::.:||:.||||||:::||.|..
Human    71 QQPTQFINPETP------GYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDL 129

  Fly    72 -------GSTPSPHNLPNVKLKANTYELQESNVRLKLTVCDTIGYGDQVNKADSYKALVEYVDSQ 129
                   |:......  .|:::|:|.|::|..|:|:|||.||.||||.:|..|.:|.::.|:|.|
Human   130 YPERVIPGAAEKIER--TVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQ 192

  Fly   130 FEAYLQEELKIQRAMASAH--DGRVHACLYFICPTGHGLKAMDLVCMKQLDTRVNIIPVIAKADT 192
            ||.||.:|..:.|    .|  |.|||.|.|||.|.|||||.:|:..||.:..:|||:||||||||
Human   193 FERYLHDESGLNR----RHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADT 253

  Fly   193 ISKSELSGFKERIMDELRRNNVSIYQFP----MDDETVSETNAAMNGHLPFAVVGSTEFVKVAGK 253
            ::..|....|:||:||:..:|:.||..|    .:||...|....:...:||:||||.:.::..||
Human   254 LTLKERERLKKRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGK 318

  Fly   254 QVRARQYPWGAVHIENEAHCDFVKLREMLIRTNMEDLREQTHTRHYELFRQRRLQQMG--FVDVD 316
            :||.|.||||.|.:||..|.||:|||.||| |:|:||:|.|...|||.||..||::.|  ..:.|
Human   319 KVRGRLYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERLKRGGRKVENED 382

  Fly   317 SNNQPVSFQQTFESKR-SDHLACLQAKEEEVRQMFVQ 352
            .|...:..::..|.:| .:.:|.:||:    .||.:|
Human   383 MNKDQILLEKEAELRRMQEMIARMQAQ----MQMQMQ 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Septin5	NP_651961.1	CDC_Septin	43..311	CDD:206649	125/280 (45%)
		COG4913	<274..>416	CDD:443941	32/82 (39%)
SEPTIN2	XP_024308688.1	Septin	102..373	CDD:395596	125/277 (45%)