Protein Alignment Sep5 and Septin8

DIOPT Version :9

• Sequence 1: NP_651961.1
• Gene: Sep5 / 43990
• FlyBaseID: FBgn0026361
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: XP_038941860.1
• Gene: Septin8 / 303135
• RGDID: 1308449
• Length: 483
• Species: Rattus norvegicus
• Alignment Length: 413
• Identity: 260/413 - (62%)
• Similarity: 320/413 - (77%)
• Gaps: 9/413 - (2%)

  Fly    18 PRLLQLGGHVGFDTLPDQLVNKSVQNGFSFNILCIGETALGKSTLMDTLFNTSFGSTPSPHNLPN 82
            ||.|.||||||||:||||||:|||..||||||||:|||.:||||||:|||||:|.:..:.|:...
  Rat    16 PRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFETEEASHHEEC 80

  Fly    83 VKLKANTYELQESNVRLKLTVCDTIGYGDQVNKADSYKALVEYVDSQFEAYLQEELKIQRAMASA 147
            |:|:..||:||||||.||||:.|.:|:|||:||.|||:.:|:|:|:|||.||||||||:|::...
  Rat    81 VRLRPQTYDLQESNVHLKLTIVDAVGFGDQINKDDSYRPIVDYIDTQFENYLQEELKIRRSLFDY 145

  Fly   148 HDGRVHACLYFICPTGHGLKAMDLVCMKQLDTRVNIIPVIAKADTISKSELSGFKERIMDELRRN 212
            ||.|:|.|||||.||||.||::|||.||:||::|||||:||||||||||||..||.:||.||..|
  Rat   146 HDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMGELVSN 210

  Fly   213 NVSIYQFPMDDETVSETNAAMNGHLPFAVVGSTEFVKVAGKQVRARQYPWGAVHIENEAHCDFVK 277
            .|.|||||.|||.|:|.||.||.|||||||||||.|||..|.|||||||||.|.:|||.||||||
  Rat   211 GVQIYQFPTDDEAVAEINAVMNAHLPFAVVGSTEEVKVGNKLVRARQYPWGVVQVENENHCDFVK 275

  Fly   278 LREMLIRTNMEDLREQTHTRHYELFRQRRLQQMGFVDVDSNNQPVSFQQTFESKRSDHLACLQAK 342
            |||||||.||||||||||:|||||:|:.:|::|||.|.|.::||.|.|:|:|:||.:.|:.||.|
  Rat   276 LREMLIRVNMEDLREQTHSRHYELYRRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRK 340

  Fly   343 EEEVRQMFVQRVKQKENELKDNEKELHTKFDRLKREHLEEKAQLEEARRQLEED-----CQELQR 402
            |||:|||||.:||:.|.|||:.|:|||.||:.|||.|.|||.::||.||:|||:     |::...
  Rat   341 EEEMRQMFVNKVKETELELKEKERELHEKFEHLKRIHQEEKRKVEEKRRELEEETNAFNCRKAAM 405

  Fly   403 RRLQM----ANGSHTLTLGRGKK 421
            ..||.    |.....|...:.||
  Rat   406 EALQSQALHATSQQPLRKDKDKK 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sep5	NP_651961.1	CDC3	25..394	CDD:227352	245/368 (67%)
		CDC_Septin	43..311	CDD:206649	182/267 (68%)
		BAR	<252..405	CDD:299863	96/157 (61%)
Septin8	XP_038941860.1	CDC_Septin	41..309	CDD:206649	182/267 (68%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	432	1.000	Domainoid score	I564
eggNOG	1	0.900	-	-		E1_COG5019
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	592	1.000	Inparanoid score	I941
OMA	1	1.010	-	-		QHG51948
OrthoDB	1	1.010	-	-		D294076at33208
OrthoFinder	1	1.000	-	-		FOG0000793
OrthoInspector	1	1.000	-	-		mtm9061
orthoMCL	1	0.900	-	-		OOG6_101834
Panther	1	1.100	-	-	O	PTHR18884
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X467
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.880