Protein Alignment Sep5 and Septin5

DIOPT Version :9

• Sequence 1: NP_651961.1
• Gene: Sep5 / 43990
• FlyBaseID: FBgn0026361
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_998779.2
• Gene: Septin5 / 18951
• MGIID: 1195461
• Length: 369
• Species: Mus musculus
• Alignment Length: 370
• Identity: 148/370 - (40%)
• Similarity: 223/370 - (60%)
• Gaps: 31/370 - (8%)

  Fly     4 LVTEKKTQEVATKVPRLLQLGGHVGFDTLPDQLVNKSVQNGFSFNILCIGETALGKSTLMDTLFN 68
            |.|.:..|::..:         :|||.|||:|:..|||:.||.|.::..||:.||||||:.:||.
Mouse    11 LATPEDKQDIDKQ---------YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFL 66

  Fly    69 TSFG------STPSPHNLPNVKLKANTYELQESNVRLKLTVCDTIGYGDQVNKADSYKALVEYVD 127
            |...      |.....| ..|::..:|.:::|..|:||||:.||.|:||.||.::.:|.:.:|||
Mouse    67 TDLYKDRKLLSAEERIN-QTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNSECWKPITDYVD 130

  Fly   128 SQFEAYLQEELKIQRAMASAHDGRVHACLYFICPTGHGLKAMDLVCMKQLDTRVNIIPVIAKADT 192
            .|||.|.::|..:.|  .:..|.|||.|||||.|.||||:.:|:..||.|..:|||:|:|||||.
Mouse   131 QQFEQYFRDESGLNR--KNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADC 193

  Fly   193 ISKSELSGFKERIMDELRRNNVSIYQFPM----DDETVSETNAAMNGHLPFAVVGSTEFVKVAGK 253
            :..||:...|:||.:|:.:..:.:||||.    :||...:.:..:....||||:||...|:..|:
Mouse   194 LVPSEIRKLKDRIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQ 258

  Fly   254 QVRARQYPWGAVHIENEAHCDFVKLREMLIRTNMEDLREQTHTRHYELFRQRRLQQM-GFVDVDS 317
            :||.|.||||.|.:||:|||||||||.|||||:|.||::.|...|||.:|...:||| ..:..||
Mouse   259 RVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTSKLTQDS 323

  Fly   318 NNQ---PVSFQQTFESKRSDHLACLQAKEEEVRQM--FVQRVKQK 357
            ..:   |:....|.:::..   ..::.|:||:|:|  .:|::||:
Mouse   324 RMESPIPILPLPTPDAETE---KLIRMKDEELRRMQEMLQKMKQQ 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sep5	NP_651961.1	CDC3	25..394	CDD:227352	145/349 (42%)
		CDC_Septin	43..311	CDD:206649	123/278 (44%)
		BAR	<252..405	CDD:299863	48/112 (43%)
Septin5	NP_998779.2	Septin	42..313	CDD:395596	120/273 (44%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	51..58		4/6 (67%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	108..111		2/2 (100%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	189..192		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5019
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D845354at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820