Protein Alignment Sep5 and unc-61

DIOPT Version :9

• Sequence 1: NP_651961.1
• Gene: Sep5 / 43990
• FlyBaseID: FBgn0026361
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_872156.2
• Gene: unc-61 / 179976
• WormBaseID: WBGene00006795
• Length: 530
• Species: Caenorhabditis elegans
• Alignment Length: 417
• Identity: 187/417 - (44%)
• Similarity: 268/417 - (64%)
• Gaps: 29/417 - (6%)

  Fly     6 TEKKTQEVATKVP-----------RLLQLGGHVGFDTLPDQLVNKSVQNGFSFNILCIGETALGK 59
            |.||....|...|           |::||.||||||:||.|||.|:|:.||.||::|:|||..||
 Worm   117 TSKKPTIAAPTAPSPIKSLSDHTGRVMQLNGHVGFDSLPHQLVKKAVEAGFQFNLMCVGETGTGK 181

  Fly    60 STLMDTLFNTSFGSTPSPHNLPNVKLKANTYELQESNVRLKLTVCDTIGYGDQVNKADSYKALVE 124
            :||:::|||......|..|.|..|:|:..|.::.|..:|:||.:.:|.|:|||::|..|.|.:|:
 Worm   182 TTLIESLFNMKLDFEPCNHELKTVELRTCTKDVAEGGIRVKLRLVETAGFGDQLDKDKSAKVIVD 246

  Fly   125 YVDSQFEAYLQEELKIQRAMASAHDGRVHACLYFICPTGHGLKAMDLVCMKQLDTRVNIIPVIAK 189
            |::||||.|||||||.:|.:...:|.|:|||||||.||||||||:|||.:::|..|||:||||||
 Worm   247 YLESQFETYLQEELKPRRMLQYFNDSRIHACLYFISPTGHGLKALDLVTLRELAKRVNVIPVIAK 311

  Fly   190 ADTISKSELSGFKERIMDELRRNNVSIYQFPMDDETVSETNAAMNGHLPFAVVGSTEFVKVA-GK 253
            :||..|.||..||.:|:.||:...:.||.||.||||||.||..||..:|||||||.:|||.. |:
 Worm   312 SDTTCKDELLRFKAKILSELKSQKIDIYTFPTDDETVSTTNKEMNKSVPFAVVGSIDFVKKENGQ 376

  Fly   254 QVRARQYPWGAVHIENEAHCDFVKLREMLIRTNMEDLREQTHTRHYELFRQRRLQQMGFVDVDSN 318
            .|||||||||.|.:|||:|||||||||.|:|||::::|::||...||.:|:.||:||...|.::.
 Worm   377 MVRARQYPWGIVEVENESHCDFVKLREALLRTNVDEMRQRTHESLYENYRRDRLRQMKIGDGETG 441

  Fly   319 NQPVSFQQTFESKRSDHLACLQAKEEEVRQMFVQRVKQKENELKD-------NEKELHTKFDRLK 376
            .:.:   :....|..:|......:|..:|:.|.:::...|.:::.       .|:|:|..::|
 Worm   442 PKII---EKLAQKHREHQDEFSRRELTLREEFQKKLDVTEGDMRKVEEGLAAREREVHENYNR-- 501

  Fly   377 REHLEEKAQLEEARRQLEEDCQELQRR 403
                 |.::|:...|||.|:..:|..:
 Worm   502 -----EASKLDMEIRQLTEERMKLMTK 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sep5	NP_651961.1	CDC3	25..394	CDD:227352	176/376 (47%)
		CDC_Septin	43..311	CDD:206649	147/268 (55%)
		BAR	<252..405	CDD:299863	55/159 (35%)
unc-61	NP_872156.2	CDC_Septin	165..434	CDD:206649	147/268 (55%)
		DUF5401	<380..530	CDD:375164	52/154 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	330	1.000	Domainoid score	I616
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	384	1.000	Inparanoid score	I1168
Isobase	1	0.950	-	0	Normalized mean entropy	S773
OMA	1	1.010	-	-		QHG51948
OrthoDB	1	1.010	-	-		D294076at33208
OrthoFinder	1	1.000	-	-		FOG0000793
OrthoInspector	1	1.000	-	-		otm14787
orthoMCL	1	0.900	-	-		OOG6_101834
Panther	1	1.100	-	-	O	PTHR18884
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X467
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.930