Protein Alignment Sep5 and SEPTIN12

DIOPT Version :9

• Sequence 1: NP_651961.1
• Gene: Sep5 / 43990
• FlyBaseID: FBgn0026361
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: XP_016878427.1
• Gene: SEPTIN12 / 124404
• HGNCID: 26348
• Length: 364
• Species: Homo sapiens
• Alignment Length: 319
• Identity: 117/319 - (36%)
• Similarity: 185/319 - (57%)
• Gaps: 33/319 - (10%)

  Fly    40 SVQNGFSFNILCIGETALGKSTLMDTLFNTSFGST-------PSPHNLPNVKLKANTYELQESNV 97
            |.|...|...:..|::.|||||:::|||.:....:       |:|..|   :|.:.|:.::|..|
Human    49 SAQRRISLGDIPRGQSGLGKSTMVNTLFKSKVWKSNPPGLGVPTPQTL---QLHSLTHVIEEKGV 110

  Fly    98 RLKLTVCDTIGYGDQVNKADSYKALVEYVDSQFEAYLQEELKIQRAMASAH--DGRVHACLYFIC 160
            :|||||.||.|:|||:|..:.:..::.|::.|:|.|||||:.|.|   ..|  |.|||.|:||:.
Human   111 KLKLTVTDTPGFGDQINNDNCWDPILGYINEQYEQYLQEEILITR---QRHIPDTRVHCCVYFVP 172

  Fly   161 PTGHGLKAMDLVCMKQLDTRVNIIPVIAKADTISKSELSGFKERIMDELRRNNVSIYQFPMDDET 225
            ||||.|:.:|:..:::|...||::||||:||:::..|...|:.||...||.:.:.:|.....||.
Human   173 PTGHCLRPLDIEFLQRLCRTVNVVPVIARADSLTMEEREAFRRRIQQNLRTHCIDVYPQMCFDED 237

  Fly   226 VSE--TNAAMNGHLPFAVVGSTEFVKVAGKQVRARQYPWGAVHIENEAHCDFVKLREMLIRTNME 288
            :::  .|:.:...:||||||:.:...|.|:.|..|:..||.:.:||.|||:|..||::|||::::
Human   238 INDKILNSKLRDRIPFAVVGADQEHLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQ 302

  Fly   289 DLREQTHTRHYELFRQRRLQQM-------GFVDVDSNNQPVSFQQ-----TFESKRSDH 335
            ||::.||..|||.:|..||.:.       |:|    |..|.|..|     ||:..|..|
Human   303 DLKDITHNIHYENYRVIRLNESHLLPRGPGWV----NLAPASPGQLTTPRTFKVCRGAH 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sep5	NP_651961.1	CDC3	25..394	CDD:227352	117/319 (37%)
		CDC_Septin	43..311	CDD:206649	105/285 (37%)
		BAR	<252..405	CDD:299863	36/96 (38%)
SEPTIN12	XP_016878427.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5019
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51948
OrthoDB	1	1.010	-	-		D845354at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.830