DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sep5 and sept7b

DIOPT Version :9

Sequence 1:	NP_651961.1	Gene:	Sep5 / 43990	FlyBaseID:	FBgn0026361	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	XP_009290954.1	Gene:	sept7b / 100000597	ZFINID:	ZDB-GENE-030131-37	Length:	425	Species:	Danio rerio

Alignment Length:	418	Identity:	168/418 - (40%)
Similarity:	260/418 - (62%)	Gaps:	21/418 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 LGGHVGFDTLPDQLVNKSVQNGFSFNILCIGETALGKSTLMDTLFNTSF--GSTPSPHN--LPNV 83
            |.|:|||.:||:|:..|||:.||.|.::.:||:.||||||:::||.|..  |..|.|.|  ...|
Zfish     7 LEGYVGFASLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSGEYPGPSNRIKKTV 71

  Fly    84 KLKANTYELQESNVRLKLTVCDTIGYGDQVNKADSYKALVEYVDSQFEAYLQEELKIQRAMASAH 148
            :::.:...::|..|:|.|::.||.|:||.|:.::.::.:::::||:||.||..|.::.|....
Zfish    72 QVEQSKVLMKEGGVQLLLSIVDTPGFGDAVDNSNCWQPVIDHIDSKFEDYLNAESRVNRRQMP-- 134

  Fly   149 DGRVHACLYFICPTGHGLKAMDLVCMKQLDTRVNIIPVIAKADTISKSELSGFKERIMDELRRNN 213
            |.|||.|||||.|:|||||.:|:..||:|..:|||||:||||||::..|...||::||.|:..:.
Zfish   135 DSRVHCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMREILEHK 199

  Fly   214 VSIYQFP-MDDETVSETNAAMNGHLPFAVVGSTEFVKVAGKQVRARQYPWGAVHIENEAHCDFVK 277
            :.||:|| .|||..::....:...||.|||||...::..||:||.||||||...:||..||||..
Zfish   200 IKIYEFPETDDEEENKIVKTIKDRLPLAVVGSNTIIEANGKKVRGRQYPWGVAEVENGDHCDFTL 264

  Fly   278 LREMLIRTNMEDLREQTHTRHYELFRQRRLQQMGFVDVDSNN-----------QPVSFQQTFESK 331
            ||.|||||:|:||::.|:..|||.:|.|:|..:....:|:|.           :.:|.....|.:
Zfish   265 LRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTCNGIDNNKAKGQLTKVDTVEGMSPLAQMEEE 329

  Fly   332 RSDHLACLQAKEEEVRQMFVQRVKQKENELKDNEKELHTKFDRLKREHLEEKAQLEEARRQLEED 396
            |.:|:..::..|.|:.|:|..:||:|..:|||:|.||..:.:::|:....:..:|||.|||.||:
Zfish   330 RREHVTKMKKMEMEMEQVFEMKVKEKVQKLKDSEGELQRRHEQMKKNLEAQHKELEERRRQFEEE 394

  Fly   397 --CQELQRRRLQMANGSHTLTLGRGKKK 422
              ..|.|:|.|:... .:.:||.:.|||
Zfish   395 RSTWETQQRILEQQK-MYVMTLEKNKKK 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sep5	NP_651961.1	CDC3	25..394	CDD:227352	156/384 (41%)
		CDC_Septin	43..311	CDD:206649	120/272 (44%)
		BAR	<252..405	CDD:299863	64/165 (39%)
sept7b	XP_009290954.1	CDC3	9..382	CDD:227352	150/374 (40%)
sept7b	XP_009290954.1	CDC_Septin	27..297	CDD:206649	120/271 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5019
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D845354at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820