Protein Alignment Sdic1 and wdr-60

DIOPT Version :9

• Sequence 1: NP_524670.2
• Gene: Sdic1 / 43984
• FlyBaseID: FBgn0067861
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_001367569.1
• Gene: wdr-60 / 175676
• WormBaseID: WBGene00016165
• Length: 668
• Species: Caenorhabditis elegans
• Alignment Length: 586
• Identity: 106/586 - (18%)
• Similarity: 199/586 - (33%)
• Gaps: 145/586 - (24%)

  Fly    26 LSVYNVQATNIPPKETLVYTKQTQTTSTGGGNGDVLAFDAQGDDEESSLQNLGNGFTSKLPPGYL 90
            |:..:::.|...||.|:. .|.:....|.....|...:....::|..:.:....|..:|| .|.:
 Worm   103 LATSHMRRTEASPKPTIA-PKISNAQITVQSTIDNKPYSYHNEEERQTQEQRAFGRLNKL-RGLI 165

  Fly    91 T--------------------HGLPTVKDVAPAITPLEIKKETEVKKEVNELSEEQKQMIILSEN 135
            :                    :.||:.|..|...|..:...| ||:.|..| :||::.....||:
 Worm   166 SIEVTKSQVFTDLSSNIFEPFNSLPSNKSHALTQTGKDCHTE-EVQTERGE-TEEKETQCPHSES 228

  Fly   136 ------------------FQRFVVRAGRVIERALSENVDIYTDYIGGGDSEEANDERSHARLSLN 182
                              .::|...|.:.|...|          |....|.|.::.|..:....:
 Worm   229 TRIEDGIEKERTSTDRARLKKFFFAATQTIREIL----------ISEDKSAEEDETREKSISKFS 283

  Fly   183 RVFYDERW------SKNRCITSMDWSTHFPELVVGSYHNNEESPNEPDGVVMVWNTKF---KKST 238
            |.:...|.      ||:.||...:     .:.|:.:| ...||| .||.:......:|   |:..
 Worm   284 RGYNPFRLCQVVTKSKSTCIRKGE-----SDSVLVAY-EIFESP-APDLINKSLIVEFFVHKRRP 341

  Fly   239 PEDVFHCQSAV----------------MSTCFAKFNPNLILGGTYSGQIVLW---DNRVQKRTP- 283
            |:.:|..:|.|                |...|..|  :|.:...:....:.|   :..:..|.|
 Worm   342 PKRLFVVESIVSVMELSQSSQILYVCLMDGTFCAF--DLSITDAFFDDNLPWVDSETNIALRRPT 404

  Fly   284 ----IQRTPLSAAAHTHPVYCLQMVGTQNAHNVISISSDGKLCSWSLDMLSQPQDTLELQ----- 339
                ...|.:|.|.   |:..:.:..:.....:.:|.:.|.:..|..:.:.:.:..|.|.
 Worm   405 FDSSFLATTVSDAT---PLIGIALGKSSVGEEITTIDTAGTISYWIANRVEKNELRLLLTAVIRP 466

  Fly   340 ----QRQSKAIAITSMAFPANEINSLVMGSEDGYVYSASRHGLRSGVNEVY---ERHLGPITGIS 397
                :|.|.:.|:::.....|.:...: |::.|.:||..:......:.::|   :...|.:|.|:
 Worm   467 HPVLKRHSTSFAVSAFCHVTNPLRFFI-GTDTGMLYSMYKSDTSQAIPKIYKTEKEKYGEVTVIA 530

  Fly   398 THYNQ---LSPDFGH-------------------LFLTSSIDWTIKLWSLKDTKPLYSFEQ---Y 437
            .:.:.   |...|.:                   ..|::.:.|.  .|||.:....|:...   .
 Worm   531 ANPSDNTVLIVGFSNGSISVYRTTQASSIVNIPTADLSTRVTWI--SWSLTNPSGFYTIHNSNII 593

  Fly   438 IAWSPVRRQRPPGPD-KTQPRHGAPALRRDSWTPSGLCIGDEAGKLYVYD----VAENLAQPSRD 497
            ..|....:..|...| :|.   ....|..|:|......||..|..|...|    |.|:.|:.:::
 Worm   594 TYWDLGFKLSPKSVDHRTD---SVQVLASDTWLSENAKIGYMAFGLSNGDSEVHVLEDPARKNQN 655

  Fly   498 E 498
            |
 Worm   656 E 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sdic1	NP_524670.2	Dynein_IC2	23..51	CDD:288403	6/24 (25%)
		NtpH	108..>178	CDD:225368	17/87 (20%)
		WD40	196..>445	CDD:295369	51/312 (16%)
		WD40	<196..442	CDD:225201	51/309 (17%)
		WD40 repeat	196..245	CDD:293791	12/51 (24%)
		WD40 repeat	251..289	CDD:293791	7/45 (16%)
		WD40 repeat	298..337	CDD:293791	3/38 (8%)
		WD40 repeat	349..386	CDD:293791	5/36 (14%)
		WD40 repeat	393..435	CDD:293791	10/63 (16%)
wdr-60	NP_001367569.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1587
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900