Protein Alignment Sdic1 and Dync1i1

DIOPT Version :9

• Sequence 1: NP_524670.2
• Gene: Sdic1 / 43984
• FlyBaseID: FBgn0067861
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: XP_006505045.1
• Gene: Dync1i1 / 13426
• MGIID: 107743
• Length: 645
• Species: Mus musculus
• Alignment Length: 525
• Identity: 253/525 - (48%)
• Similarity: 329/525 - (62%)
• Gaps: 73/525 - (13%)

  Fly    26 LSVYNVQATNIPPKETLVYTKQTQTTSTGGGNGDVLAFDAQGDDEESSLQNLGNGFTSKLPPGYL 90
            |.|..|...:..|:|.:.|:|:|||.         ||.....:|||..
Mouse   148 LGVSKVTQVDFLPREVVSYSKETQTP---------LATHQSEEDEEDE----------------- 186

  Fly    91 THGLPTVKDVAPAI---TPLEIKKETEVKKEV--NELSEEQKQMIILSENFQRFVVRAGRVIERA 150
                   :.|.|.|   :.||.:::.:..||.  .||:||:||.|:.||.|..|..|..||||||
Mouse   187 -------EMVEPKIGHDSELENQEKKQETKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERA 244

  Fly   151 LSENVDIYTDYIGGGDSEEANDERSHARLSLNRVFYDERWSKNRCITSMDWSTHFPELVVGSYHN 215
            |:|:.||:.||.|....|:..|.::.|.||.||.||||.|||:|.:|.||||..:|||:|.||.|
Mouse   245 LAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYSN 309

  Fly   216 NEESPNEPDGVVMVWNTKFKKSTPEDVFHCQSAVMSTCFAKFNPNLILGGTYSGQIVLWDNRVQK 280
            ||::|:|||||.:|||.||||:|||.||||||:|||.|||:|:|||::||||||||||||||..:
Mouse   310 NEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHR 374

  Fly   281 RTPIQRTPLSAAAHTHPVYCLQMVGTQNAHNVISISSDGKLCSWSLDMLSQPQDTLELQQRQSKA 345
            |||:||||||||||||||||:.:||||||||:|::|:|||:|||||||||.||:::||...:||.
Mouse   375 RTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKP 439

  Fly   346 IAITSMAFPANEINSLVMGSEDGYVYSASRHGLRSGVNEVYERHLGPITGISTHYNQLSPDFGHL 410
            :|:|.||||..::|:.|:|||:|.||:|.|||.::|:.||:|.|.||:|||:.|......||.||
Mouse   440 VAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHL 504

  Fly   411 FLTSSIDWTIKLWSLKDTKPLYSFEQY------IAWSPVRRQRPPG------------------- 450
            |:|||.|||:|||:.|..|||||||..      :.||||.    |.
Mouse   505 FVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVH----PALFACVDGMGRLDLWNLNSD 565

  Fly   451 ---PDKTQPRHGAPALRRDSWTPSG--LCIGDEAGKLYVYDVAENLAQPSRDEWSRFNTHLSEIK 510
               |..:....||.||.|..|...|  :.:||..|::::|||.| ||.|..|||:||...|.||:
Mouse   566 TEVPTASVAIEGASALNRVRWAQGGKEVAVGDSEGRIWIYDVGE-LAVPHNDEWTRFARTLVEIR 629

  Fly   511 MNQGD 515
            .|:.|
Mouse   630 ANRAD 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sdic1	NP_524670.2	Dynein_IC2	23..51	CDD:288403	9/24 (38%)
		NtpH	108..>178	CDD:225368	30/71 (42%)
		WD40	196..>445	CDD:295369	162/254 (64%)
		WD40	<196..442	CDD:225201	159/251 (63%)
		WD40 repeat	196..245	CDD:293791	32/48 (67%)
		WD40 repeat	251..289	CDD:293791	28/37 (76%)
		WD40 repeat	298..337	CDD:293791	27/38 (71%)
		WD40 repeat	349..386	CDD:293791	19/36 (53%)
		WD40 repeat	393..435	CDD:293791	24/41 (59%)
Dync1i1	XP_006505045.1	Dynein_IC2	147..173	CDD:371592	9/24 (38%)
		WD40	283..606	CDD:392136	178/326 (55%)
		WD40 repeat	291..337	CDD:293791	30/45 (67%)
		WD40 repeat	346..385	CDD:293791	29/38 (76%)
		WD40 repeat	393..434	CDD:293791	28/40 (70%)
		WD40 repeat	442..481	CDD:293791	20/38 (53%)
		WD40 repeat	488..529	CDD:293791	24/40 (60%)
		WD40 repeat	535..573	CDD:293791	6/41 (15%)
		WD40 repeat	581..607	CDD:293791	8/25 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830606
Domainoid	1	1.000	379	1.000	Domainoid score	I846
eggNOG	1	0.900	-	-		E1_KOG1587
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	638	1.000	Inparanoid score	I823
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54336
OrthoDB	1	1.010	-	-		D1453532at2759
OrthoFinder	1	1.000	-	-		FOG0001314
OrthoInspector	1	1.000	-	-		mtm8761
orthoMCL	1	0.900	-	-		OOG6_101571
Panther	1	1.100	-	-	O	PTHR12442
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X812
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.770