Protein Alignment Oamb and TAAR2

DIOPT Version :10

• Sequence 1: NP_001262774.1
• Gene: Oamb / 43982
• FlyBaseID: FBgn0024944
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_001028252.1
• Gene: TAAR2 / 9287
• HGNCID: 4514
• Length: 351
• Species: Homo sapiens
• Alignment Length: 570
• Identity: 102/570 - (17%)
• Similarity: 158/570 - (27%)
• Gaps: 297/570 - (52%)

  Fly    33 LVIGGNCLVIAAVFCSNKLRSVTNFFIVNLAVADLLVGLAVLPFSATWEVFKVWIFGDLWCRIWL 97
            :.|.||..:|.::....:|.:.|||.|:::|:.|.|:|..::|:|....|...|.||..:|:|:.
Human    56 ITIFGNLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYY 120

  Fly    98 AVDVWMCTASILNLCAISLDRYVAVTRPVTYPSIMSTKKAKSLIAGIWVLSFFICFPPLVGWKDQ 162
            :.|:.:...||.:||::::||:.|:..|:.|.:.::....|.|:...|.:.....|
Human   121 SFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAF--------- 176

  Fly   163 KAVIQPTYPKGNHTLYYTTTMSSSEDGQLGLDSIKDQGEASLPPSPPHIGNGNAYNPYDPGFAPI 227
            ..|....|..|                                                     |
Human   177 GVVFSEAYADG-----------------------------------------------------I 188

  Fly   228 DGSAEIRIAAIDSTSTSTTATTTTTASSSSTTETEMDLDLLNAPPQNRPQTISGSCP------WK 286
            :|                                   .|:|.|        .|.|||      |
Human   189 EG-----------------------------------YDILVA--------CSSSCPVMFNKLW- 209

  Fly   287 CELTNDRGYVLYSALGSFYIPMFVMLFFYWRIYRAAVRTTRAINQGFKTTKGSKGIGSRFEEQRL 351
                   |..|:.|  .|:.|..:|:..|.:|:..:.:...|||
Human   210 -------GTTLFMA--GFFTPGSMMVGIYGKIFAVSRKHAHAIN--------------------- 244

  Fly   352 TLRIHRGRGSNQQDSMHSNGSTQSTTTTLGTPSPERLSKYATRRLHHHDKIKISVSYPSSENISE 416
                                                                             
Human   245 ----------------------------------------------------------------- 244

  Fly   417 LAGHGDVGHERRQSGNALFAVHYNGTNGRESTESQLYRQQQQHGVASSCYLQVGKGLPELARRQS 481
                                      |.||:                                |:
Human   245 --------------------------NLREN--------------------------------QN 251

  Fly   482 NTSEAGGSGHSRPANKKMGRRNIKAQVKRFRMETKAAKTLAIIVGMFIFCWCPFFTMYIIRPFCQ 546
            |                        |||:   :.||||||.|::|:|:.||.|.|...::.||..
Human   252 N------------------------QVKK---DKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLN 289

  Fly   547 DCVDPLLFSVLFWLGYCNSAVNPMIYALFSKDFRFAFK-----RIICRCF 591
            .....:||..|.|.||.||..||:||..|...||.|.|     :|...||
Human   290 FSTPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCF 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oamb	NP_001262774.1	7tmA_Octopamine_R	21..583	CDD:320191	97/555 (17%)
		TM helix 1	22..48	CDD:320191	4/14 (29%)
		TM helix 2	55..81	CDD:320191	10/25 (40%)
		TM helix 3	93..123	CDD:320191	10/29 (34%)
		TM helix 4	135..158	CDD:320191	4/22 (18%)
		TM helix 5	292..321	CDD:320191	8/28 (29%)
		TM helix 6	512..542	CDD:320191	13/29 (45%)
		TM helix 7	551..576	CDD:320191	12/24 (50%)
TAAR2	NP_001028252.1	7tmA_TAAR2_3_4	44..326	CDD:320437	97/555 (17%)
		TM helix 1	45..71	CDD:320437	4/14 (29%)
		TM helix 2	78..104	CDD:320437	10/25 (40%)
		TM helix 3	116..146	CDD:320437	10/29 (34%)
		TM helix 4	158..181	CDD:320437	5/31 (16%)
		TM helix 5	206..235	CDD:320437	9/38 (24%)
		TM helix 6	255..285	CDD:320437	14/32 (44%)
		TM helix 7	294..319	CDD:320437	12/24 (50%)