Protein Alignment Oamb and Htr7

DIOPT Version :9

• Sequence 1: NP_001262774.1
• Gene: Oamb / 43982
• FlyBaseID: FBgn0024944
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: XP_038945768.1
• Gene: Htr7 / 65032
• RGDID: 71034
• Length: 508
• Species: Rattus norvegicus
• Alignment Length: 601
• Identity: 147/601 - (24%)
• Similarity: 209/601 - (34%)
• Gaps: 271/601 - (45%)

  Fly    25 AVLEFINVLVIGGNCLVIAAVFCSNKLRSVTNFFIVNLAVADLLVGLAVLPF-SATWEVFKVWIF 88
            ::|..|.:|.|.|||||:.:|....|||..:|:.||:||:|||.|.:||:|| |.|..:...|||
  Rat    89 SILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIF 153

  Fly    89 GDLWCRIWLAVDVWMCTASILNLCAISLDRYVAVTRPVTYPSIMSTKKAKSLIAGIWVLSFFICF 153
            |..:|.:::|:||..|||||:.||.||:|||:.:|||:|||...:.|....:|..:|:||..|..
  Rat   154 GHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITL 218

  Fly   154 PPLVGWKDQKAVIQPTYPKGNHTLYYTTTMSSSEDGQLGLDSIKDQGEASLPPSPPHIGNGNAYN 218
            |||.||                                                        |.|
  Rat   219 PPLFGW--------------------------------------------------------AQN 227

  Fly   219 PYDPGFAPIDGSAEIRIAAIDSTSTSTTATTTTTASSSSTTETEMDLDLLNAPPQNRPQTISGSC 283
            ..|                 |..
  Rat   228 VND-----------------DKV------------------------------------------ 233

  Fly   284 PWKCELTNDRGYVLYSALGSFYIPMFVMLFFYWRIYRAAVRTTRAINQ--GFKTTKGSKGIGSRF 346
               |.::.|.||.:||...:|||||.||||.|::||:|| |.:.|.::  ||...
  Rat   234 ---CLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAA-RKSAAKHKFPGFPRV---------- 284

  Fly   347 EEQRLTLRIHRGRGSNQQDSMHS-NGSTQSTTTTLGTPSPERLSKYATRRLHHHDKIKISVSYPS 410
                            |.:|:.| ||                             .:|:......
  Rat   285 ----------------QPESVISLNG-----------------------------VVKLQKEVEE 304

  Fly   411 SENISELAGHGDVGHERRQSGNALFAVHYNGTNGRESTESQLYRQQQQHGVASSCYLQVGKGLPE 475
            ..|:|.|     :.|||:
  Rat   305 CANLSRL-----LKHERK----------------------------------------------- 317

  Fly   476 LARRQSNTSEAGGSGHSRPANKKMGRRNIKAQVKRFRMETKAAKTLAIIVGMFIFCWCPFFTMYI 540
                                           .:..|:.|.|||.||.||||.|..||.|||.:..
  Rat   318 -------------------------------NISIFKREQKAATTLGIIVGAFTVCWLPFFLLST 351

  Fly   541 IRPF-----CQDCVDPLLFSVLFWLGYCNSAVNPMIYALFSKDFRFAFKRIICRCFCSRQSVSLK 600
            .|||     | .|:...:.....||||.||.:||.|||.|::|.|..::.::   .|..::::.|
  Rat   352 ARPFICGTSC-SCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLL---QCQYRNINRK 412

  Fly   601 SSRRGSDMSAIRIRAR 616
            .|..|.. .|:::..|
  Rat   413 LSAAGMH-EALKLAER 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oamb	NP_001262774.1	7tm_4	29..>154	CDD:304433	59/125 (47%)
		7tm_1	37..>181	CDD:278431	61/144 (42%)
Htr7	XP_038945768.1	7tmA_5-HT7	100..398	CDD:320452	137/555 (25%)
		TM helix 2	120..142	CDD:320452	13/21 (62%)
		TM helix 3	159..181	CDD:320452	11/21 (52%)
		TM helix 4	204..220	CDD:320452	5/15 (33%)
		TM helix 5	240..263	CDD:320452	13/22 (59%)
		TM helix 6	329..351	CDD:320452	13/21 (62%)
		TM helix 7	366..391	CDD:320452	11/24 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24247
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010