Protein Alignment Oamb and Htr1f

DIOPT Version :9

• Sequence 1: NP_001262774.1
• Gene: Oamb / 43982
• FlyBaseID: FBgn0024944
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_068629.2
• Gene: Htr1f / 60448
• RGDID: 71083
• Length: 366
• Species: Rattus norvegicus
• Alignment Length: 586
• Identity: 136/586 - (23%)
• Similarity: 209/586 - (35%)
• Gaps: 237/586 - (40%)

  Fly     7 EDLIKSVKWTEPANLISLAVLEFINVLVIGGNCLVIAAVFCSNKLRSVTNFFIVNLAVADLLVGL 71
            |:|:..:    |:.::....|..:.::....|.|||.|:..:.||....|:.|.:|||.|.||.:
  Rat    14 EELLNRM----PSKILVSLTLSGLALMTTTINSLVITAIIVTRKLHHPANYLICSLAVTDFLVAV 74

  Fly    72 AVLPFSATWEVFKVWIFGDLWCRIWLAVDVWMCTASILNLCAISLDRYVAVTRPVTYPSIMSTKK 136
            .|:|||..:.|.:.||.|...|.:||:||:..|:.|||:|.||:||||.|:|..|.|....:.:.
  Rat    75 LVMPFSIVYIVSESWIMGQGLCDLWLSVDIICCSCSILHLSAIALDRYRAITDAVEYARKRTPRH 139

  Fly   137 AKSLIAGIWVLSFFICFPPLVGWKDQKAVIQPTYPKGNHTLYYTTTMSSSEDGQLGLDSIKDQGE 201
            |...|..:||:|.||..|||. |:.|          ||           |.|.|
  Rat   140 AGITITTVWVISVFISMPPLF-WRHQ----------GN-----------SRDDQ----------- 171

  Fly   202 ASLPPSPPHIGNGNAYNPYDPGFAPIDGSAEIRIAAIDSTSTSTTATTTTTASSSSTTETEMDLD 266
                                                                             
  Rat   172 ----------------------------------------------------------------- 171

  Fly   267 LLNAPPQNRPQTISGSCPWKCELTNDR-GYVLYSALGSFYIPMFVMLFFYWRIYRAAVRTTRAIN 330
                                |.:.:|. ...:||..|:||||:.::|..|::||||| ||.....
  Rat   172 --------------------CIIKHDHIVSTIYSTFGAFYIPLVLILILYYKIYRAA-RTLYHKR 215

  Fly   331 QGFKTTKGSKGIGSRFEEQRLTLRIHRGRGSNQQDSMHSNGSTQSTTTTLGTPSPERLSKYATRR 395
            |..:..|         ||....:.:..|     :.|:....::.....:|..||.:
  Rat   216 QASRMIK---------EELNGQVLLESG-----EKSIKLVSTSYMLEKSLSDPSTD--------- 257

  Fly   396 LHHHDKIKISVSYPSSENISELAGHGDVGHERRQSGNALFAVHYNGTNGRESTESQLYRQQQQHG 460
               .|:|..:|..|.||          :.||:.                        :|:|:..|
  Rat   258 ---FDRIHSTVKSPRSE----------LKHEKS------------------------WRRQKISG 285

  Fly   461 VASSCYLQVGKGLPELARRQSNTSEAGGSGHSRPANKKMGRRNIKAQVKRFRMETKAAKTLAIIV 525
            .                                                   .|.|||.||.:|:
  Rat   286 T---------------------------------------------------RERKAATTLGLIL 299

  Fly   526 GMFIFCWCPFFTMYIIRPFCQDC-VDPLLFSVLFWLGYCNSAVNPMIYALFSKDFRFAFKRIICR 589
            |.|:.||.|||...::...|:.| :...:.:.|.||||.||.:||:||.:|::||:.||:::: |
  Rat   300 GAFVICWLPFFVKELVVNICEKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQKLV-R 363

  Fly   590 C 590
            |
  Rat   364 C 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oamb	NP_001262774.1	7tm_4	29..>154	CDD:304433	50/124 (40%)
		7tm_1	37..>181	CDD:278431	57/143 (40%)
Htr1f	NP_068629.2	7tm_1	41..347	CDD:278431	123/535 (23%)
		7tm_4	41..>222	CDD:304433	79/299 (26%)
		Agonist binding. /evidence=ECO:0000250	99..108		4/8 (50%)
		DRY motif, important for ligand-induced conformation changes. /evidence=ECO:0000250	120..122		1/1 (100%)
		Agonist binding. /evidence=ECO:0000250	306..310		2/3 (67%)
		NPxxY motif, important for ligand-induced conformation changes and signaling. /evidence=ECO:0000250	343..347		2/3 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910