Protein Alignment Oamb and htr7a

DIOPT Version :10

• Sequence 1: NP_001262774.1
• Gene: Oamb / 43982
• FlyBaseID: FBgn0024944
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: XP_021328829.2
• Gene: htr7a / 562111
• ZFINID: ZDB-GENE-130530-666
• Length: 479
• Species: Danio rerio
• Alignment Length: 630
• Identity: 154/630 - (24%)
• Similarity: 234/630 - (37%)
• Gaps: 247/630 - (39%)

  Fly     2 NETECEDLIKSVKWTEPANLISLAVLEFINVLVIGGNCLVIAAVFCSNKLRSVTNFFIVNLAVAD 66
            |.|.|.:.|.|  :.|...::...||..:.::.|.||.||:.:|....|||..:|:.||:||:||
Zfish    88 NGTRCAEQILS--YGEVEKVLIGGVLTMLTLITICGNMLVVISVCFVKKLRQPSNYLIVSLALAD 150

  Fly    67 LLVGLAVLPF-SATWEVFKVWIFGDLWCRIWLAVDVWMCTASILNLCAISLDRYVAVTRPVTYPS 130
            |.|.|||:|| |.|..:...||||..:|.:::|:||..|||||:.||.||:|||:.:|||:|||.
Zfish   151 LSVALAVMPFVSITDLIGGRWIFGKFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPV 215

  Fly   131 IMSTKKAKSLIAGIWVLSFFICFPPLVGWKDQKAVIQPTYPKGNHTLYYTTTMSSSEDGQLGLDS 195
            ..:......::..:|:||..|..|||.||
Zfish   216 RQNGWCMAKMVLSVWLLSASITLPPLFGW------------------------------------ 244

  Fly   196 IKDQGEASLPPSPPHIGNGNAYNPYDPGFAPIDGSAEIRIAAIDSTSTSTTATTTTTASSSSTTE 260
                                |.|..|.           |:
Zfish   245 --------------------AQNVNDD-----------RV------------------------- 253

  Fly   261 TEMDLDLLNAPPQNRPQTISGSCPWKCELTNDRGYVLYSALGSFYIPMFVMLFFYWRIYRAA-VR 324
                                      |.::.|.||.:||...:|||||.|||..|:||:||| :.
Zfish   254 --------------------------CLISQDFGYTIYSTAVAFYIPMTVMLVMYYRIFRAAKLS 292

  Fly   325 TTRAINQGFKTTKGSKGIGSRFEEQRLTLRIHRGRGSNQQDSMHSNGSTQSTTTTLGTPSPERLS 389
            ..:....||          .|.|::.:           ::|.:..:|..       |...|..:
Zfish   293 AAKHTITGF----------PRVEQEEV-----------EEDEVEEDGGD-------GAEEPTGV- 328

  Fly   390 KYATRRLHHHDKIKISVSYPSSENISELAGHGDVGHERRQSGNALFAVHYNGTNGRESTESQLYR 454
                      |.:.:::                                            :|.|
Zfish   329 ----------DCVTVAI--------------------------------------------KLQR 339

  Fly   455 QQQQHGVASSCYLQVGKGLPELARRQSNTSEAGGSGHSRPANKKMGRR-NIKAQVKRFRMETKAA 518
            :.::      |     ..||.:.|                   .:||| :.:..:..|:.|.|||
Zfish   340 EVEE------C-----ARLPRILR-------------------GVGRRCSDRRSISIFKREQKAA 374

  Fly   519 KTLAIIVGMFIFCWCPFFTMYIIRPF-----CQDCVDPLLFSVLFWLGYCNSAVNPMIYALFSKD 578
            .||.|:||.|..||.|||.:...|||     | .|:...:...|.||||.||.:||.|||.|::|
Zfish   375 ATLGIVVGAFTICWLPFFLLSTARPFICGTEC-SCIPLWVERTLLWLGYANSLINPFIYAFFNRD 438

  Fly   579 FRFAFKRIICRCFCSRQSVSLKSSRRGSDMSAIRIRARTPSITPS 623
            .|..::.::.   |..::::.:.|..|.. .|:|:..| |.:..|
Zfish   439 LRTTYRSLLS---CRYRNINRRLSAAGMH-EALRLVER-PEVVVS 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oamb	NP_001262774.1	7tmA_Octopamine_R	21..583	CDD:320191	140/569 (25%)
		TM helix 1	22..48	CDD:320191	8/25 (32%)
		TM helix 2	55..81	CDD:320191	16/26 (62%)
		TM helix 3	93..123	CDD:320191	16/29 (55%)
		TM helix 4	135..158	CDD:320191	7/22 (32%)
		TM helix 5	292..321	CDD:320191	16/28 (57%)
		TM helix 6	512..542	CDD:320191	15/29 (52%)
		TM helix 7	551..576	CDD:320191	12/24 (50%)
htr7a	XP_021328829.2	None