Protein Alignment Oamb and adra1ab

DIOPT Version :10

• Sequence 1: NP_001262774.1
• Gene: Oamb / 43982
• FlyBaseID: FBgn0024944
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: XP_021334987.2
• Gene: adra1ab / 557259
• ZFINID: ZDB-GENE-060503-384
• Length: 431
• Species: Danio rerio
• Alignment Length: 692
• Identity: 170/692 - (24%)
• Similarity: 239/692 - (34%)
• Gaps: 298/692 - (43%)

  Fly     7 EDLIKSVKWTEP-ANLISLAVLEF--INVLVIG------------GNCLVIAAVFCSNKLRSVTN 56
            ||.|.|..:.|. :|..::..||.  ...||:|            ||.|||.:|.|...|||||:
Zfish     8 EDYINSTFFPENCSNCSTIPALEIDVTKTLVLGLVLVLFLIFGVMGNILVILSVACHRNLRSVTH 72

  Fly    57 FFIVNLAVADLLVGLAVLPFSATWEVFKVWIFGDLWCRIWLAVDVWMCTASILNLCAISLDRYVA 121
            :||.|||:||||:...||||||..|....|:||...|..|.|:||..||||||:||.||:||.:|
Zfish    73 YFIGNLAIADLLLSSVVLPFSAVSEALGRWVFGRHLCNAWTALDVLCCTASILSLCVISVDRCMA 137

  Fly   122 VTRPVTYPSIMSTKKAKSLIAGIWVLSFFICFPPLVGWKDQKAVIQPTYPKGNHTLYYTTTMSSS 186
            |:.|:.|||..:.::|.:.:|.:|.||..|...||.||::
Zfish   138 VSYPLQYPSFATGRRAMTAVAALWALSAAISVGPLFGWRE------------------------- 177

  Fly   187 EDGQLGLDSIKDQGEASLPPSPPHIGNGNAYNPYDPGFAPIDGSAEIRIAAIDSTSTSTTATTTT 251
                               |.|.                  |.|.
Zfish   178 -------------------PMPE------------------DESV-------------------- 185

  Fly   252 TASSSSTTETEMDLDLLNAPPQNRPQTISGSCPWKCELTNDRGYVLYSALGSFYIPMFVMLFFYW 316
                                               |.:..|.||.::||..|||:|:.|:|..|.
Zfish   186 -----------------------------------CRVNEDPGYAIFSAACSFYVPLAVILAMYC 215

  Fly   317 RIYRAAVRTTRAINQGFKTTKGSKGIGSRFEEQRLTLRIHRGRGSNQQDSMHSNGSTQSTTTTLG 381
            |:|..|...|||:::. :.|.|       ..||.:|||||..:..|.
Zfish   216 RVYVVARHKTRAMSKS-RETNG-------LSEQGMTLRIHCRKAQND------------------ 254

  Fly   382 TPSPERLSKYATRRLHHHDKIKISVSYPSSENISELAGHGDVGHERRQSGNALFAVHYNGTNGRE 446
                       ||:   .|.:::.                          |:.||.
Zfish   255 -----------TRK---EDAMRLK--------------------------NSHFAF--------- 270

  Fly   447 STESQLYRQQQQHGVASSCYLQVGKGLPELARRQSNTSEAGGSGHSRPANKKMGRRNIKAQVKRF 511
                                                                       .::.:|
Zfish   271 -----------------------------------------------------------MRLLKF 276

  Fly   512 RMETKAAKTLAIIVGMFIFCWCPFFTMYII-------RPFCQDCVDPLLFSVLFWLGYCNSAVNP 569
            ..|.||||||.|:||.|:.||.|||.:..|       ||  .|.|    |.:.|||||.||.:||
Zfish   277 SREKKAAKTLGIVVGCFVLCWLPFFLVLPISSIFPSHRP--PDAV----FKITFWLGYFNSCLNP 335

  Fly   570 MIYALFSKDFRFAFKRII-CRCFCSRQSVSLKSSRRGSDMSAIRIRARTPSITPSAAAHSFGDES 633
            :||..||::|:.||:.:: .||      :|..........:|.:...::|....|....|:..:.
Zfish   336 IIYPCFSQEFKKAFQNVLHGRC------LSRTHQTWSPPANATQYMPKSPQGLSSGFTDSWRSDH 394

  Fly   634 ELHHSEMSNDPRXRSFGPSSSSQSSLGGLRKTSLKVPVYEIC 675
            ....:.|.|:   .|:....:|         .||||....||
Zfish   395 ASSSAVMLNE---NSYDEPDTS---------LSLKVHQVSIC 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oamb	NP_001262774.1	7tmA_Octopamine_R	21..583	CDD:320191	145/582 (25%)
		TM helix 1	22..48	CDD:320191	11/39 (28%)
		TM helix 2	55..81	CDD:320191	16/25 (64%)
		TM helix 3	93..123	CDD:320191	18/29 (62%)
		TM helix 4	135..158	CDD:320191	8/22 (36%)
		TM helix 5	292..321	CDD:320191	14/28 (50%)
		TM helix 6	512..542	CDD:320191	17/36 (47%)
		TM helix 7	551..576	CDD:320191	12/24 (50%)
adra1ab	XP_021334987.2	None