Protein Alignment Oamb and htr5ab

DIOPT Version :10

• Sequence 1: NP_001262774.1
• Gene: Oamb / 43982
• FlyBaseID: FBgn0024944
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_001007122.1
• Gene: htr5ab / 368475
• ZFINID: ZDB-GENE-030616-574
• Length: 346
• Species: Danio rerio
• Alignment Length: 577
• Identity: 121/577 - (20%)
• Similarity: 199/577 - (34%)
• Gaps: 262/577 - (45%)

  Fly    18 PANLISLAVLEFINVLVIG---GNCLVIAAVFCSNKLRSVTNFFIVNLAVADLLVGLAVLPFSAT 79
            |.::.|:..|..:.:||:.   .|.||:..:........|.:..:.::|::|::|...|:|.|..
Zfish    25 PFSVFSVLTLTLLAMLVVATFVWNLLVLVTILRVRTFHRVPHNLVASMAISDVMVAGLVMPLSLV 89

  Fly    80 WEVF-KVWIFGDLWCRIWLAVDVWMCTASILNLCAISLDRYVAVTRPVTYPSIMSTKKAKSLIAG 143
            .|:: :.||.|...|::|::.||..|||||.|:.||:||||.::||.:.| ::.:.|:..:::.|
Zfish    90 RELYGRRWILGRALCQVWISCDVLCCTASIWNVTAIALDRYWSITRHLEY-TLKTRKRISNVMIG 153

  Fly   144 I-WVLSFFICFPPLVGWKDQKAVIQPTYPKGNHTLYYTTTMSSSEDGQLGLDSIKDQGEASLPPS 207
            : |:||..|...||.||.:       ||               |||              ||
Zfish   154 LTWLLSSVISLSPLFGWGE-------TY---------------SED--------------SL--- 179

  Fly   208 PPHIGNGNAYNPYDPGFAPIDGSAEIRIAAIDSTSTSTTATTTTTASSSSTTETEMDLDLLNAPP 272
                                                                             
Zfish   180 ----------------------------------------------------------------- 179

  Fly   273 QNRPQTISGSCPWKCELTNDRGYVLYSALGSFYIPMFVMLFFYWRIYRAAVRTTRAINQGFKTTK 337
                         .|:::.:..|.::|..|:||:|:.|:||.||:||:||
Zfish   180 -------------ACQVSQEPSYTVFSTFGAFYLPLCVVLFVYWKIYKAA--------------- 216

  Fly   338 GSKGIGSRFEEQRLTLRIHRGRGSNQQDSMHSNGSTQSTTTTLGTPSPERLSKYATRRLHHHDKI 402
                          ..||               ||.::.|.|
Zfish   217 --------------KFRI---------------GSRKTNTIT----------------------- 229

  Fly   403 KISVSYPSSENISELAGHGDVGHERRQSGNALFAVHYNGTNGRESTESQLYRQQQQHGVASSCYL 467
                  |.:|.|       :|....||...| |.|.:...:.:  |:.:.:|:|:
Zfish   230 ------PMAEVI-------EVKEAERQPQMA-FTVRHATVSFQ--TDGETWREQK---------- 268

  Fly   468 QVGKGLPELARRQSNTSEAGGSGHSRPANKKMGRRNIKAQVKRFRMETKAAKTLAIIVGMFIFCW 532
                                                          |.:||..:.|::|:|:.||
Zfish   269 ----------------------------------------------ERRAALMVGILIGVFVLCW 287

  Fly   533 CPFFTMYIIRPFCQDCVDPLLFSVLFWLGYCNSAVNPMIYALFSKDFRFAFKRIICR 589
            .|||...:|.|.|...:.|:..||..||||.||..||:||..|:|::..||:.:..|
Zfish   288 IPFFLAELIIPLCSCDIPPVWKSVFLWLGYSNSFFNPLIYTAFNKNYNNAFRNLFSR 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oamb	NP_001262774.1	7tmA_Octopamine_R	21..583	CDD:320191	117/566 (21%)
		TM helix 1	22..48	CDD:320191	7/28 (25%)
		TM helix 2	55..81	CDD:320191	6/25 (24%)
		TM helix 3	93..123	CDD:320191	16/29 (55%)
		TM helix 4	135..158	CDD:320191	8/23 (35%)
		TM helix 5	292..321	CDD:320191	13/28 (46%)
		TM helix 6	512..542	CDD:320191	11/29 (38%)
		TM helix 7	551..576	CDD:320191	13/24 (54%)
htr5ab	NP_001007122.1	7tmA_5-HT5	31..338	CDD:320451	116/563 (21%)
		TM helix 1	32..58	CDD:320451	6/25 (24%)
		TM helix 2	65..91	CDD:320451	6/25 (24%)
		TM helix 3	104..134	CDD:320451	16/29 (55%)
		TM helix 4	146..167	CDD:320451	5/20 (25%)
		TM helix 5	186..215	CDD:320451	13/28 (46%)
		TM helix 6	267..297	CDD:320451	12/85 (14%)
		TM helix 7	306..331	CDD:320451	13/24 (54%)