| Sequence 1: | NP_001262774.1 | Gene: | Oamb / 43982 | FlyBaseID: | FBgn0024944 | Length: | 751 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_000857.1 | Gene: | HTR1F / 3355 | HGNCID: | 5292 | Length: | 366 | Species: | Homo sapiens |
| Alignment Length: | 593 | Identity: | 138/593 - (23%) |
|---|---|---|---|
| Similarity: | 210/593 - (35%) | Gaps: | 249/593 - (41%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 7 EDLIKSVKWTEPANLISLAVLEFINVLVIGGNCLVIAAVFCSNKLRSVTNFFIVNLAVADLLVGL 71
Fly 72 AVLPFSATWEVFKVWIFGDLWCRIWLAVDVWMCTASILNLCAISLDRYVAVTRPVTYPSIMSTKK 136
Fly 137 AKSLIAGIWVLSFFICFPPLVGWKDQKAVIQPTYPKGNHTLYYTTTMSSSEDGQLGLDSIKDQGE 201
Fly 202 ASLPPSPPHIGNGNAYNPYDPGFAPIDGSAEIRIAAIDSTSTSTTATTTTTASSSSTTETEMDLD 266
Fly 267 LLNAPPQNRPQTISGSCPWKCELTNDR-GYVLYSALGSFYIPMFVMLFFYWRIYRAAVRTTRAIN 330
Fly 331 QGFKTTKGSKGIGSRFEEQRLTLRIHRGRGSNQQDSMHSNGSTQSTTT------TLGTPSPERLS 389
Fly 390 KYATRRLHHHDKIKISVSYPSSENISELAGHGDVGHERRQSGNALFAVHYNGTNGRESTESQLYR 454
Fly 455 QQQQHGVASSCYLQVGKGLPELARRQSNTSEAGGSGHSRPANKKMGRRNIKAQVKRFRMETKAAK 519
Fly 520 TLAIIVGMFIFCWCPFFTMYIIRPFCQDC-VDPLLFSVLFWLGYCNSAVNPMIYALFSKDFRFAF 583
Fly 584 KRII-CRC 590 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Oamb | NP_001262774.1 | 7tm_4 | 29..>154 | CDD:304433 | 53/124 (43%) |
| 7tm_1 | 37..>181 | CDD:278431 | 58/143 (41%) | ||
| HTR1F | NP_000857.1 | 7tmA_5-HT1F | 24..359 | CDD:320456 | 131/570 (23%) |
| TM helix 1 | 26..50 | CDD:320456 | 7/23 (30%) | ||
| TM helix 2 | 59..81 | CDD:320456 | 11/21 (52%) | ||
| TM helix 3 | 97..119 | CDD:320456 | 13/21 (62%) | ||
| Agonist binding. /evidence=ECO:0000250 | 99..108 | 4/8 (50%) | |||
| DRY motif, important for ligand-induced conformation changes. /evidence=ECO:0000250 | 120..122 | 1/1 (100%) | |||
| TM helix 4 | 142..158 | CDD:320456 | 5/15 (33%) | ||
| TM helix 5 | 179..202 | CDD:320456 | 8/22 (36%) | ||
| TM helix 6 | 292..314 | CDD:320456 | 11/21 (52%) | ||
| Agonist binding. /evidence=ECO:0000250 | 306..310 | 2/3 (67%) | |||
| TM helix 7 | 326..351 | CDD:320456 | 11/24 (46%) | ||
| NPxxY motif, important for ligand-induced conformation changes and signaling. /evidence=ECO:0000250 | 343..347 | 2/3 (67%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||