| Sequence 1: | NP_001262774.1 | Gene: | Oamb / 43982 | FlyBaseID: | FBgn0024944 | Length: | 751 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_000856.1 | Gene: | HTR1E / 3354 | HGNCID: | 5291 | Length: | 365 | Species: | Homo sapiens |
| Alignment Length: | 604 | Identity: | 143/604 - (23%) |
|---|---|---|---|
| Similarity: | 210/604 - (34%) | Gaps: | 257/604 - (42%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1 MNETECED----LIKSVKWTEPANL-ISLAVLEFINVLVIGGNCLVIAAVFCSNKLRSVTNFFIV 60
Fly 61 NLAVADLLVGLAVLPFSATWEVFKVWIFGDLWCRIWLAVDVWMCTASILNLCAISLDRYVAVTRP 125
Fly 126 VTYPSIMSTKKAKSLIAGIWVLSFFICFPPLVGWKDQKAVIQPTYPKGNHTLYYTTTMSSSEDGQ 190
Fly 191 LGLDSIKDQGEASLPPSPPHIGNGNAYNPYDPGFAPIDGSAEIRIAAIDSTSTSTTATTTTTASS 255
Fly 256 SSTTETEMDLDLLNAPPQNRPQTISGSCPWKCELTNDRG-YVLYSALGSFYIPMFVMLFFYWRIY 319
Fly 320 RAAVRTTRAINQGFKTTKGSKGIGSRFEEQRLTLRIHRGRGSNQQDSMHSNGSTQSTTT------ 378
Fly 379 TLGTPSPERLSKYATRRLHHHDKIKISVSYPSSENISELAGHGDVGH--ERRQSGNALFAVHYNG 441
Fly 442 TNGRESTESQLYRQQQQHGVASSCYLQVGKGLPELARRQSNTSEAGGSGHSRPANKKMGRRNIKA 506
Fly 507 QVKRFRMETKAAKTLAIIVGMFIFCWCPFFTMYIIRPFCQDCVDPLLFSVLFWLGYCNSAVNPMI 571
Fly 572 YALFSKDFRFAFKRII-CR 589 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Oamb | NP_001262774.1 | 7tm_4 | 29..>154 | CDD:304433 | 49/124 (40%) |
| 7tm_1 | 37..>181 | CDD:278431 | 52/143 (36%) | ||
| HTR1E | NP_000856.1 | 7tmA_5-HT1E | 23..355 | CDD:320457 | 130/573 (23%) |
| TM helix 1 | 24..50 | CDD:320457 | 7/28 (25%) | ||
| TM helix 2 | 57..83 | CDD:320457 | 12/25 (48%) | ||
| TM helix 3 | 95..125 | CDD:320457 | 18/29 (62%) | ||
| Agonist binding. /evidence=ECO:0000250 | 98..107 | 4/8 (50%) | |||
| DRY motif, important for ligand-induced conformation changes. /evidence=ECO:0000250 | 119..121 | 1/1 (100%) | |||
| TM helix 4 | 137..159 | CDD:320457 | 9/21 (43%) | ||
| TM helix 5 | 179..208 | CDD:320457 | 14/28 (50%) | ||
| TM helix 6 | 284..314 | CDD:320457 | 13/77 (17%) | ||
| Agonist binding. /evidence=ECO:0000250 | 304..308 | 2/3 (67%) | |||
| TM helix 7 | 323..348 | CDD:320457 | 10/24 (42%) | ||
| NPxxY motif, important for ligand-induced conformation changes and signaling. /evidence=ECO:0000250 | 340..344 | 2/3 (67%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||