| Sequence 1: | NP_001262774.1 | Gene: | Oamb / 43982 | FlyBaseID: | FBgn0024944 | Length: | 751 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_000855.1 | Gene: | HTR1D / 3352 | HGNCID: | 5289 | Length: | 377 | Species: | Homo sapiens |
| Alignment Length: | 594 | Identity: | 145/594 - (24%) |
|---|---|---|---|
| Similarity: | 205/594 - (34%) | Gaps: | 249/594 - (41%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1 MNETECEDLIKSVKWTEPANL----ISLA-VLEFINVLVIGGNCLVIAAVFCSNKLRSVTNFFIV 60
Fly 61 NLAVADLLVGLAVLPFSATWEVFKVWIFGDLWCRIWLAVDVWMCTASILNLCAISLDRYVAVTRP 125
Fly 126 VTYPSIMSTKKAKSLIAGIWVLSFFICFPPLVGWKDQKAVIQPTYPKGNHTLYYTTTMSSSEDGQ 190
Fly 191 LGLDSIKDQGEASLPPSPPHIGNGNAYNPYDPGFAPIDGSAEIRIAAIDSTSTSTTATTTTTASS 255
Fly 256 SSTTETEMDLDLLNAPPQNRPQTISGSCPWKCELTNDRGYVLYSALGSFYIPMFVMLFFYWRIYR 320
Fly 321 AAVRTTRAINQGFKTTKGSKGIGSRFEEQRLTLRIHRGRGSNQQDSMHSNGSTQSTTTTLGTPSP 385
Fly 386 ERLSKYATRRLHHHDKIKISVSYPSSENISELAGHGDVGHERRQSGNALFAVHYNGTNGRESTES 450
Fly 451 QLYRQQQQHGVASSCYLQVGKGLPELARRQSNTSEAGGSGHSRPANKKMGRRNIKAQVKRFRMET 515
Fly 516 KAAKTLAIIVGMFIFCWCPFFTMYIIRPFCQD-C-VDPLLFSVLFWLGYCNSAVNPMIYALFSKD 578
Fly 579 FRFAFKRII 587 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Oamb | NP_001262774.1 | 7tm_4 | 29..>154 | CDD:304433 | 46/124 (37%) |
| 7tm_1 | 37..>181 | CDD:278431 | 51/143 (36%) | ||
| HTR1D | NP_000855.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..23 | 1/2 (50%) | |
| 7tmA_5-HT1B_1D | 35..367 | CDD:320455 | 135/567 (24%) | ||
| TM helix 1 | 40..66 | CDD:320455 | 8/25 (32%) | ||
| TM helix 2 | 73..99 | CDD:320455 | 11/25 (44%) | ||
| TM helix 3 | 111..141 | CDD:320455 | 19/29 (66%) | ||
| Agonist binding. /evidence=ECO:0000250 | 114..123 | 3/8 (38%) | |||
| DRY motif, important for ligand-induced conformation changes. /evidence=ECO:0000250 | 135..137 | 1/1 (100%) | |||
| TM helix 4 | 153..176 | CDD:320455 | 9/23 (39%) | ||
| TM helix 5 | 194..223 | CDD:320455 | 12/28 (43%) | ||
| TM helix 6 | 294..324 | CDD:320455 | 15/29 (52%) | ||
| Agonist binding. /evidence=ECO:0000250 | 314..318 | 2/3 (67%) | |||
| TM helix 7 | 335..360 | CDD:320455 | 13/24 (54%) | ||
| NPxxY motif, important for ligand-induced conformation changes and signaling. /evidence=ECO:0000250 | 352..356 | 2/3 (67%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||