| Sequence 1: | NP_001262774.1 | Gene: | Oamb / 43982 | FlyBaseID: | FBgn0024944 | Length: | 751 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_000854.1 | Gene: | HTR1B / 3351 | HGNCID: | 5287 | Length: | 390 | Species: | Homo sapiens |
| Alignment Length: | 573 | Identity: | 139/573 - (24%) |
|---|---|---|---|
| Similarity: | 200/573 - (34%) | Gaps: | 238/573 - (41%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 18 PANLISLAVLEFINVLVIGGNCLVIAAVFCSNKLRSVTNFFIVNLAVADLLVGLAVLPFSATWEV 82
Fly 83 FKVWIFGDLWCRIWLAVDVWMCTASILNLCAISLDRYVAVTRPVTYPSIMSTKKAKSLIAGIWVL 147
Fly 148 SFFICFPPLVGWKDQKAVIQPTYPKGNHTLYYTTTMSSSEDGQLGLDSIKDQGEASLPPSPPHIG 212
Fly 213 NGNAYNPYDPGFAPIDGSAEIRIAAIDSTSTSTTATTTTTASSSSTTETEMDLDLLNAPPQNRPQ 277
Fly 278 TISGSCPWKCELTNDR-GYVLYSALGSFYIPMFVMLFFYWRIYRAAVRTTRAINQGFKTTKGSKG 341
Fly 342 IGSRFEEQRLTLRIHRGRGSNQQDSMHSNGSTQSTTTTLGTPSPERLSKYATRRLHHHDKIKISV 406
Fly 407 SYPSSENISELAGHGDVGHERRQSGNALFAVHYNGTNGRESTESQLYRQQQQHGVASSCYLQVGK 471
Fly 472 GLPELARRQSNTSEAGGSGHSRPANKKMGRRNIKAQVKRFRMETKAAKTLAIIVGMFIFCWCPFF 536
Fly 537 TMYIIRPFCQD-CVDPL-LFSVLFWLGYCNSAVNPMIYALFSKDFRFAFKRII 587 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Oamb | NP_001262774.1 | 7tm_4 | 29..>154 | CDD:304433 | 52/124 (42%) |
| 7tm_1 | 37..>181 | CDD:278431 | 56/143 (39%) | ||
| HTR1B | NP_000854.1 | 7tmA_5-HT1B_1D | 46..380 | CDD:320455 | 136/567 (24%) |
| TM helix 1 | 51..77 | CDD:320455 | 7/25 (28%) | ||
| TM helix 2 | 84..110 | CDD:320455 | 12/25 (48%) | ||
| TM helix 3 | 122..152 | CDD:320455 | 18/29 (62%) | ||
| Agonist binding | 125..134 | 3/8 (38%) | |||
| DRY motif, important for ligand-induced conformation changes and signaling | 146..148 | 1/1 (100%) | |||
| TM helix 4 | 164..187 | CDD:320455 | 10/23 (43%) | ||
| TM helix 5 | 205..234 | CDD:320455 | 11/34 (32%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 259..281 | 9/61 (15%) | |||
| TM helix 6 | 307..337 | CDD:320455 | 17/40 (43%) | ||
| Agonist binding | 327..331 | 2/3 (67%) | |||
| TM helix 7 | 348..373 | CDD:320455 | 12/24 (50%) | ||
| NPxxY motif, important for ligand-induced conformation changes and signaling | 365..369 | 2/3 (67%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||