Protein Alignment Oamb and ser-6

DIOPT Version :9

• Sequence 1: NP_001262774.1
• Gene: Oamb / 43982
• FlyBaseID: FBgn0024944
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_741350.1
• Gene: ser-6 / 259560
• WormBaseID: WBGene00021897
• Length: 401
• Species: Caenorhabditis elegans
• Alignment Length: 575
• Identity: 147/575 - (25%)
• Similarity: 221/575 - (38%)
• Gaps: 192/575 - (33%)

  Fly    21 LISLAVLEFINVLVIGGNCLVIAAVFCSNKLRSVTNFFIVNLAVADLLVGLAVLPFSATWEVFKV 85
            |:|| .|..:|..|:.||.||...:.....|::.||..:::|.::|||:|:.:|||:...|....
 Worm     3 LLSL-TLGVVNCFVVIGNLLVFYVILTKKSLQTSTNHLVLSLTISDLLLGILILPFAIIQEHSNE 66

  Fly    86 WIFGDLWCRIWLAVDVWMCTASILNLCAISLDRYVAVTRPVTYPSIMSTKKAKSLIAGIWVLSFF 150
            ||||...||:||:|||::.||||.||.|||.|||:||.:|:.||.|.|||..:.:...:|..|..
 Worm    67 WIFGHFGCRLWLSVDVFLSTASIYNLLAISFDRYMAVRQPIKYPIISSTKVVRLMTFLVWFCSLL 131

  Fly   151 ICFPPLVGWKDQKAVIQPTYPKGNHTLYYTTTMSSSEDGQLGLDSIKDQGEASLPPSPPHIGNGN 215
            :            |||          |:...|:::.:.     :..||....|||..
 Worm   132 L------------AVI----------LFVLLTLNAHDS-----EPTKDCQPTSLPSM-------- 161

  Fly   216 AYNPYDPGFAPIDGSAEIRIAAIDSTSTSTTATTTTTASSSSTTETEMDLDLLNAPPQNRPQTIS 280
                                                                             
 Worm   162 ----------------------------------------------------------------- 161

  Fly   281 GSCPWKCELTNDRGYVLYSALGSFYIPMFVMLFFYWRIYRAAVRTTRAINQGFKTTKGSKGIGSR 345
                          |:::||:.||.:|.|||:....||::..:.|:|.:     |.|...|
 Worm   162 --------------YIIFSAMASFIVPAFVMVILNVRIFQTVLHTSRTM-----TVKSKNG---- 203

  Fly   346 FEEQRLTLRIHRGRGSNQQDSMHSNGSTQSTTTTLGTPSPERLSKYATRRLHHHDKIKISVSYPS 410
                  :||:||.:........|                    .||.||..|..:    .|..||
 Worm   204 ------SLRVHRRKEPIIPVKKH--------------------DKYETRLSHEEE----CVGSPS 238

  Fly   411 SENISELAGHGDVGHERRQSGNALFAVHYNGTNGRESTESQLYRQQQQH----GVASSCYLQVGK 471
            .|.|..:.....|....:.|                :.::...|....|    ||..:....:..
 Worm   239 KEVIDPIPVVAVVEKHHKSS----------------AVDAPAIRSFLTHTVVFGVLEAKKTNIIN 287

  Fly   472 GLPELARRQSNTSEAGGSGHSRPANKKMGRRNIKAQVKRFRMETKAAKTLAIIVGMFIFCWCPFF 536
            .:.:..||.:..|       ..|:.:|      |...:..|.|.:.|:|..|:|..||.||.||.
 Worm   288 HITQWWRRSTVRS-------PNPSTRK------KCMRRSLRTEIRVARTTGIVVAAFIVCWIPFT 339

  Fly   537 TMYIIRPF-----CQDCVDPLLFSVLFWLGYCNSAVNPMIYALFSKDFRFAFKRI 586
            |:|:::.:     ...|:...||:..|||||.||||||::||.||:|||.|.||:
 Worm   340 TIYVLQAYAVCTVAAGCIPASLFTTAFWLGYSNSAVNPILYAAFSRDFRIALKRL 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oamb	NP_001262774.1	7tm_4	29..>154	CDD:304433	52/124 (42%)
		7tm_1	37..>181	CDD:278431	54/143 (38%)
ser-6	NP_741350.1	7tmA_amine_R-like	3..391	CDD:320098	144/570 (25%)
		TM helix 1	4..28	CDD:320098	9/24 (38%)
		TM helix 2	37..59	CDD:320098	9/21 (43%)
		TM helix 3	75..97	CDD:320098	14/21 (67%)
		TM helix 4	120..136	CDD:320098	5/37 (14%)
		TM helix 5	159..183	CDD:320098	10/110 (9%)
		TM helix 6	318..343	CDD:320098	11/24 (46%)
		TM helix 7	359..384	CDD:320098	15/24 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_112839
Panther	1	1.100	-	-	LDO	PTHR24247
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910