Protein Alignment Oamb and Gpr161

DIOPT Version :10

• Sequence 1: NP_001262774.1
• Gene: Oamb / 43982
• FlyBaseID: FBgn0024944
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_001074595.1
• Gene: Gpr161 / 240888
• MGIID: 2685054
• Length: 558
• Species: Mus musculus
• Alignment Length: 630
• Identity: 120/630 - (19%)
• Similarity: 196/630 - (31%)
• Gaps: 275/630 - (43%)

  Fly    25 AVLEFINVLVIG-----GNCLVIAAVFCSNKLRSVTNFFIVNLAVADLLVGLAVLPFSATWEVFK 84
            ||.|||.:::|.     ||.:::..::..:.|.:::|.|:.:|.:::.|:.:.||||..|..:.:
Mouse    56 AVSEFIAIIIITVLVCLGNLVIVVTLYKKSYLLTLSNKFVFSLTLSNFLLSVLVLPFVVTSSIRR 120

  Fly    85 VWIFGDLWCRIWLAVDVWMCTASILNLCAISLDRYVAVTRPVTYPSIMSTKKAKSLIAGIWVLSF 149
            .||||.:||.....:.:.:.:||:|.|..|::|||.||..|:.||..::..:|...:..||:.|.
Mouse   121 EWIFGVVWCNFSALLYLLISSASMLTLGVIAIDRYYAVLYPMVYPMKITGNRAVMALVYIWLHSL 185

  Fly   150 FICFPPLVGWKDQKAVIQPTYPKGNHTLYYTTTMSSSEDGQLGLDSIKDQGEASLPPSPPHIGNG 214
            ..|.|||.||                        ||.|     .|..|
Mouse   186 IGCLPPLFGW------------------------SSVE-----FDEFK----------------- 204

  Fly   215 NAYNPYDPGFAPIDGSAEIRIAAIDSTSTSTTATTTTTASSSSTTETEMDLDLLNAPPQNRPQTI 279
                                                                             
Mouse   205 ----------------------------------------------------------------- 204

  Fly   280 SGSCPWKCELT--NDRGYVLYSALGSFYIPMFVMLFFYWRIYRAAVRTTRAINQGFKTTKGSKGI 342
                 |.|...  .:.||.::..:.....|..:||..|..|:|.|....|.::.|...|.
Mouse   205 -----WMCVAAWHQEPGYTIFWQIWCALFPFLIMLVCYGFIFRVARVKARKVHCGTVVTV----- 259

  Fly   343 GSRFEEQRLTLRIHRGRGSNQQDSMHSNGSTQSTTTTLGTPSPERLSKYATRRLHHHDKIKISVS 407
                                ::||..|.....||:|          |...:||
Mouse   260 --------------------EEDSQRSGRKNSSTST----------SSSGSRR------------ 282

  Fly   408 YPSSENISELAGHGDVGHERRQSGNALFAVHYNGTNGRESTESQLYRQQQQHGVASSCYLQVGKG 472
                                    |||..|.|:                     |:.|
Mouse   283 ------------------------NALQGVVYS---------------------ANQC------- 295

  Fly   473 LPELARRQSNTSEAGGSGHSRPANKKMGRRNIKAQVKRFRMETKAAKTLAIIVGMFIFCWCPFFT 537
                                                       ||..|:.:::|.|:..|.|:
Mouse   296 -------------------------------------------KALITILVVIGAFMVTWGPY-- 315

  Fly   538 MYIIRP---FCQDCVDPLLFSVLFWLGYCNSAVNPMIYALFSKDFRFAFKRIICRCFCSR-QSVS 598
            |.:|..   :.::||.|.|.:...||.:.::..:|:||.|::|..|   |.::..||..| ...|
Mouse   316 MVVITSEALWGKNCVSPTLETWATWLSFTSAICHPLIYGLWNKTVR---KELLGMCFGDRYYRES 377

  Fly   599 LKSSRRGSDMSAIRIRARTPSITPSAAAHSFGDESELHHSEMSND 643
            ....:|.|.:.:|..|.....::|...|...|.:| |.||..:.|
Mouse   378 FVQRQRTSRLFSISNRITDLGLSPHLTALMAGGQS-LGHSSSTGD 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oamb	NP_001262774.1	7tmA_Octopamine_R	21..583	CDD:320191	103/567 (18%)
		TM helix 1	22..48	CDD:320191	8/27 (30%)
		TM helix 2	55..81	CDD:320191	9/25 (36%)
		TM helix 3	93..123	CDD:320191	10/29 (34%)
		TM helix 4	135..158	CDD:320191	8/22 (36%)
		TM helix 5	292..321	CDD:320191	7/28 (25%)
		TM helix 6	512..542	CDD:320191	8/29 (28%)
		TM helix 7	551..576	CDD:320191	8/24 (33%)
Gpr161	NP_001074595.1	7tmA_GPR161	58..364	CDD:320342	102/568 (18%)
		TM helix 1	58..84	CDD:320342	6/25 (24%)
		TM helix 2	91..116	CDD:320342	8/24 (33%)
		TM helix 3	129..159	CDD:320342	10/29 (34%)
		TM helix 4	171..193	CDD:320342	7/21 (33%)
		TM helix 5	214..243	CDD:320342	7/28 (25%)
		TM helix 6	292..322	CDD:320342	11/81 (14%)
		TM helix 7	332..357	CDD:320342	8/24 (33%)