Protein Alignment Oamb and dop-3

DIOPT Version :10

• Sequence 1: NP_001262774.1
• Gene: Oamb / 43982
• FlyBaseID: FBgn0024944
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_001024908.2
• Gene: dop-3 / 188499
• WormBaseID: WBGene00020506
• Length: 607
• Species: Caenorhabditis elegans
• Alignment Length: 716
• Identity: 171/716 - (23%)
• Similarity: 261/716 - (36%)
• Gaps: 242/716 - (33%)

  Fly     4 TECEDLIKSVKWTEPANLISLAVLEFINVLVIGGNCLVIAAVFCSNKLRSVTNFFIVNLAVADLL 68
            |:.|..:..|.|...|.:.    |..:..:.:.||.|||.:||....|::|||..||:|||:|.:
 Worm     9 TDIESPLMVVLWRVAAGVF----LPLVPTMAVFGNVLVIMSVFRERSLQTVTNMLIVSLAVSDFM 69

  Fly    69 VGLAVLPFSA--TWEVFKVWIFGDLWCRIWLAVDVWMCTASILNLCAISLDRYVAVTRPVTYPSI 131
            |.:.|:.|..  .|..|| |..|..:|.::.|:||...|||||||.|||||||:|:..|::|...
 Worm    70 VAIGVMSFGVYYEWNDFK-WGLGSFFCHVYQALDVACSTASILNLLAISLDRYIAIGHPISYAQY 133

  Fly   132 ----------------MSTKKAKSLIAGI----------------------WVLSFFI-CFPPLV 157
                            :|...|..|:.|:                      .:.|||| |...::
 Worm   134 GARGGRAMISITIVWGVSVAVALPLLLGVNPMEENDLQECELANPYFNMISSIFSFFIPCIAMII 198

  Fly   158 GW-------------------------KDQKAVI---QPTYPKGNH---------------TLYY 179
            .:                         |...|::   |.....|.|               |..:
 Worm   199 LYTIIFRRLRQRERARSLRQAQRSENDKISSALLGGAQIARQMGKHFKNRTDQILLEISFQTSSF 263

  Fly   180 TTTMSSSEDGQLGLDSIKDQGEASLPPSPPHIGNGNAYNPYDPGFAPIDGSAEIRIAAIDSTSTS 244
            .|...||||.            :::.|..      |::|.:.|...|...::   |.||....:.
 Worm   264 PTMSESSEDA------------STISPMI------NSFNNFLPKKTPYPSTS---IPAIPECGSM 307

  Fly   245 TTATTTTTASSSSTTETEMDLDLLNAPPQNRPQTISGSCPWKCELTNDRGYVLYSALGSFYIPMF 309
            ...|......:....|..: :||.:.                .|:.:|:
 Worm   308 PNLTIIERPEAEKEKEISI-MDLRDT----------------VEMLDDK---------------- 339

  Fly   310 VMLFFYWRIYRAAVRTTRAINQGFKTTKGSKGIGSRFEEQRLTLRIHRGRGS--NQQDSMHSNGS 372
                     |.:|:.|:      |:|   |:..|...||   .|....|..|  :.::.:|:..|
 Worm   340 ---------YSSAILTS------FQT---SRSFGEELEE---ILPFIDGSNSVKHSREQLHTTRS 383

  Fly   373 TQSTTTTLGTPSPERLSKYATRRLHHHDKIKISVSYPSSENISELAGHGDVGHERRQSGNALFAV 437
            ..|||..|......|                 |:|.||.::..:|:          |..|.|...
 Worm   384 NTSTTRLLDVKPELR-----------------SISVPSIQDEKKLS----------QKSNDLPFS 421

  Fly   438 HYNG-----------------------TNGRESTESQLYRQQQQHGVAS---------SCYLQVG 470
            |.||                       |||...|:| |.|...:..:|.         |..::|.
 Worm   422 HQNGTHKQKLLPNPGILMKSKSTTLLKTNGYMDTDS-LNRNSHKKSLADLLANDEFSFSDSMRVY 485

  Fly   471 KGLPELARRQSNTSEAGGSGHSRPANKKMGRRNIKAQVKRFRMETKAAKTLAIIVGMFIFCWCPF 535
            |      .|...:.....||.::|   :..|..:|...|:.|.|.||..|||:::.:|:|||.||
 Worm   486 K------NRLFKSLSRATSGWNKP---RPSRHMVKKATKQMRREHKATVTLAVVLAVFLFCWLPF 541

  Fly   536 FTMYIIRPFC------QDCVDPLLFSVLFWLGYCNSAVNPMIYALFSKDFRFAFKRII-CRCFCS 593
            |.:::....|      ..||..|...:..||||.||::||:||.:|.:.||.||:.|: |..|..
 Worm   542 FVLHLSNSICLIIDENSACVGFLPLYLATWLGYLNSSLNPLIYTVFDQRFRNAFRNILSCGIFKK 606

  Fly   594 R 594
            |
 Worm   607 R 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oamb	NP_001262774.1	7tmA_Octopamine_R	21..583	CDD:320191	160/685 (23%)
		TM helix 1	22..48	CDD:320191	8/25 (32%)
		TM helix 2	55..81	CDD:320191	11/27 (41%)
		TM helix 3	93..123	CDD:320191	19/29 (66%)
		TM helix 4	135..158	CDD:320191	8/45 (18%)
		TM helix 5	292..321	CDD:320191	2/28 (7%)
		TM helix 6	512..542	CDD:320191	14/29 (48%)
		TM helix 7	551..576	CDD:320191	11/24 (46%)
dop-3	NP_001024908.2	7tmA_D2-like_dopamine_R	22..>204	CDD:320181	57/186 (31%)
		TM helix 1	23..49	CDD:320181	9/29 (31%)
		TM helix 2	56..82	CDD:320181	11/25 (44%)
		TM helix 3	95..125	CDD:320181	19/29 (66%)
		TM helix 4	138..161	CDD:320181	3/22 (14%)
		TM helix 5	177..204	CDD:320181	5/26 (19%)
		7tm_GPCRs	<515..595	CDD:475119	32/79 (41%)
		TM helix 6	524..546	CDD:410628	10/21 (48%)
		TM helix 7	563..588	CDD:410628	11/24 (46%)