Protein Alignment Oamb and ser-2

DIOPT Version :10

• Sequence 1: NP_001262774.1
• Gene: Oamb / 43982
• FlyBaseID: FBgn0024944
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_001024339.1
• Gene: ser-2 / 182110
• WormBaseID: WBGene00004777
• Length: 455
• Species: Caenorhabditis elegans
• Alignment Length: 584
• Identity: 142/584 - (24%)
• Similarity: 228/584 - (39%)
• Gaps: 203/584 - (34%)

  Fly    17 EPANLISLA--VLEFINVLVI-----GGNCLVIAAVFCSNKLRSVTNFFIVNLAVADLLVGLAVL 74
            :|.::|...  ||..|..|||     .||.||:.|||....|:.|.|:|:|:||.:||.|.:.|:
 Worm    47 KPPSIIPTVELVLGTITYLVIIAMTVVGNTLVVVAVFSYRPLKKVQNYFLVSLAASDLAVAIFVM 111

  Fly    75 PFS-ATWEVFKVWIFGDLWCRIWLAVDVWMCTASILNLCAISLDRYVAVTRPVTYPSIMSTKKAK 138
            |.. .|:.....|:.|...|:.:...|:.:||:||||||||:||||.|:..|:.|....:||...
 Worm   112 PLHVVTFLAGGKWLLGVTVCQFFTTADILLCTSSILNLCAIALDRYWAIHNPINYAQKRTTKFVC 176

  Fly   139 SLIAGIWVLSFFICFPPLVGWKDQKAVIQPTYPKGNHTLYYTTTMSSSEDGQLGLDSIKDQGEAS 203
            .:|..:|:||..|..||::||.:.:.                   :..||
 Worm   177 IVIVIVWILSMLISVPPIIGWNNWQE-------------------NMMED--------------- 207

  Fly   204 LPPSPPHIGNGNAYNPYDPGFAPIDGSAEIRIAAIDSTSTSTTATTTTTASSSSTTETEMDLDLL 268
                                                                             
 Worm   208 ----------------------------------------------------------------- 207

  Fly   269 NAPPQNRPQTISGSCPWKCELTNDRGYVLYSALGSFYIPMFVMLFFYWRIYRAAVRTTRAINQGF 333
                             .|.|:.::.:|::||.|||::|:.||:..|.:|:.:|       .|..
 Worm   208 -----------------SCGLSTEKAFVVFSAAGSFFLPLLVMVVVYVKIFISA-------RQRI 248

  Fly   334 KTTKGSKGIGSRFEEQRLTLRIHRGRGSNQQDSMH-SNGSTQS--TTTTLGTPSPERLSKYATRR 395
            :|.:|...:          :||....|.:....|. ...|.:|  |::.:|..:|..::...|
 Worm   249 RTNRGRSAL----------MRIQNAEGDDDYRKMSIKRASVESARTSSRVGEKTPLVIADGQT-- 301

  Fly   396 LHHHDKIKISVSYPSSENISELAGHGDVGHERRQSGNALFAVHYNGTNGRESTESQLYRQQQQHG 460
                             .::.||.|                    .|:|....:.:..:..:.|.
 Worm   302 -----------------TVTTLAAH--------------------STDGGSLPKDETTKHMKYHN 329

  Fly   461 VASSCYLQVGKGLPELARRQSNTSEAGGSGHSRPANKKMGRRNIKAQVKRFRMETKAAKTLAIIV 525
             ..||.::| |.:.|            ..|:..|.  .:.|:..|..|.:   |.:||||:|:|:
 Worm   330 -NGSCKVKV-KDVKE------------DEGNPNPT--AVLRKREKISVAK---EKRAAKTIAVII 375

  Fly   526 GMFIFCWCPFFTMYIIRPFCQDC-VDPLLFSVLFWLGYCNSAVNPMIYALFSKDFRFAFKRIIC 588
            .:|.|||.|||..|:|||||:.| :...:.....||||.||::||.:|.:.:.:||.|||:|:|
 Worm   376 FVFSFCWLPFFVAYVIRPFCETCKLHAKVEQAFTWLGYINSSLNPFLYGILNLEFRRAFKKILC 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oamb	NP_001262774.1	7tmA_Octopamine_R	21..583	CDD:320191	136/573 (24%)
		TM helix 1	22..48	CDD:320191	14/32 (44%)
		TM helix 2	55..81	CDD:320191	11/26 (42%)
		TM helix 3	93..123	CDD:320191	17/29 (59%)
		TM helix 4	135..158	CDD:320191	8/22 (36%)
		TM helix 5	292..321	CDD:320191	11/28 (39%)
		TM helix 6	512..542	CDD:320191	15/29 (52%)
		TM helix 7	551..576	CDD:320191	9/24 (38%)
ser-2	NP_001024339.1	7tmA_tyramine_octopamine_R-like	58..434	CDD:320188	135/566 (24%)
		TM helix 1	59..85	CDD:320188	12/25 (48%)
		TM helix 2	92..118	CDD:320188	10/25 (40%)
		TM helix 3	131..161	CDD:320188	17/29 (59%)
		TM helix 4	173..196	CDD:320188	8/22 (36%)
		TM helix 5	214..243	CDD:320188	11/28 (39%)
		TM helix 6	362..392	CDD:320188	15/32 (47%)
		TM helix 7	402..427	CDD:320188	9/24 (38%)