Protein Alignment Oamb and Htr5a

DIOPT Version :9

• Sequence 1: NP_001262774.1
• Gene: Oamb / 43982
• FlyBaseID: FBgn0024944
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: XP_006535694.1
• Gene: Htr5a / 15563
• MGIID: 96283
• Length: 380
• Species: Mus musculus
• Alignment Length: 580
• Identity: 122/580 - (21%)
• Similarity: 192/580 - (33%)
• Gaps: 269/580 - (46%)

  Fly    21 LISLAVLEFINVLVIGGNCLVIAAVFCSNKLRSVTNFFIVNLAVADLLVGLAVLPFSATWEVF-K 84
            ::.|.:|.|:.......|.||:|.:........|.:..:.::|::|:||.:.|:|.|...|:. :
Mouse    64 VLVLTLLGFLAAATFTWNLLVLATILKVRTFHRVPHNLVASMAISDVLVAVLVMPLSLVHELSGR 128

  Fly    85 VWIFGDLWCRIWLAVDVWMCTASILNLCAISLDRYVAVTRPVTYPSIMSTKKAKS--LIAGIWVL 147
            .|..|...|::|:|.||..|||||.|:.||:||||.::||.:.|  .:.|:|..|  :|...|.|
Mouse   129 RWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHLEY--TLRTRKRVSNVMILLTWAL 191

  Fly   148 SFFICFPPLV-GWKDQKAVIQPTYPKGNHTLYYTTTMSSSEDGQLGLDSIKDQGEASLPPSPPHI 211
            |..|...||: ||                                        ||....||.
Mouse   192 STVISLAPLLFGW----------------------------------------GETYSEPSE--- 213

  Fly   212 GNGNAYNPYDPGFAPIDGSAEIRIAAIDSTSTSTTATTTTTASSSSTTETEMDLDLLNAPPQNRP 276
                                                                             
Mouse   214 ----------------------------------------------------------------- 213

  Fly   277 QTISGSCPWKCELTNDRGYVLYSALGSFYIPMFVMLFFYWRIYRAAVRTTRAINQGFKTTKGSKG 341
                     :|:::.:..|.::|.:|:||:|:.|:||.||:|||||
Mouse   214 ---------ECQVSREPSYTVFSTVGAFYLPLCVVLFVYWKIYRAA------------------- 250

  Fly   342 IGSRFEEQRLTLRIHRGRGSNQQDSMHSNGSTQSTTTTLGTPSPERLS-KYATRRLHHHDKIKIS 405
               :|.           .||.:.:|:              :|.||.:. |.||:    |.::..:
Mouse   251 ---KFR-----------MGSRKTNSV--------------SPVPEAVEVKNATQ----HPQMVFT 283

  Fly   406 VSYPSSENISELAGHGDVGHERRQSGNALFAVHYNGTNGRESTESQLYRQQQQHGVASSCYLQVG 470
            |.            |..|..:                     ||...:|:|:
Mouse   284 VR------------HATVTFQ---------------------TEGDTWREQK------------- 302

  Fly   471 KGLPELARRQSNTSEAGGSGHSRPANKKMGRRNIKAQVKRFRMETKAAKTLAIIVGMFIFCWCPF 535
                                                       |.:||..:.|::|:|:.||.||
Mouse   303 -------------------------------------------EQRAALMVGILIGVFVLCWFPF 324

  Fly   536 FTMYIIRPFCQDCVDPLLFSVLFWLGYCNSAVNPMIYALFSKDFRFAFKRIICRCFCSRQ 595
            |...:|.|.|...|..:..|:..||||.||..||:||..|::.:..|||     .|.|:|
Mouse   325 FVTELISPLCSWDVPAIWKSIFLWLGYSNSFFNPLIYTAFNRSYSSAFK-----VFFSKQ 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oamb	NP_001262774.1	7tm_4	29..>154	CDD:304433	44/127 (35%)
		7tm_1	37..>181	CDD:278431	47/147 (32%)
Htr5a	XP_006535694.1	7tmA_5-HT5	64..372	CDD:320451	116/566 (20%)
		TM helix 1	66..90	CDD:320451	7/23 (30%)
		TM helix 2	99..121	CDD:320451	6/21 (29%)
		TM helix 3	138..160	CDD:320451	12/21 (57%)
		TM helix 4	183..199	CDD:320451	5/15 (33%)
		TM helix 5	221..244	CDD:320451	9/22 (41%)
		TM helix 6	304..329	CDD:320451	10/24 (42%)
		TM helix 7	340..365	CDD:320451	11/24 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910