Protein Alignment Oamb and Dop2R

DIOPT Version :10

• Sequence 1: NP_001262774.1
• Gene: Oamb / 43982
• FlyBaseID: FBgn0024944
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: XP_061499915.1
• Gene: Dop2R / 1274598
• VectorBaseID: AGAMI1_010373
• Length: 659
• Species: Anopheles gambiae
• Alignment Length: 634
• Identity: 166/634 - (26%)
• Similarity: 255/634 - (40%)
• Gaps: 204/634 - (32%)

  Fly    26 VLEFINVLVIGGNCLVIAAVFCSNKLRSVTNFFIVNLAVADLLVGLAVLPFSATWEVFKVWIFGD 90
            :|....:|.:.||.|||.||.....|::|||:|||:||:|||||.:.|:||:....|...|...:
Mosquito   155 ILVLFPILTLFGNVLVILAVCRERTLQTVTNYFIVSLAIADLLVAVVVMPFAVYVLVNGAWTLPN 219

  Fly    91 LWCRIWLAVDVWMCTASILNLCAISLDRYVAVTRPVTYPSIMSTKKAKSLIAGIWVLSFFICFPP 155
            ..|..::|:||...|:||.||.|||:|||:|||:|:.|....::::              :|...
Mosquito   220 FACDFYIAMDVICSTSSIFNLVAISIDRYIAVTQPIKYAKHKNSRR--------------VCLTI 270

  Fly   156 LVGWKDQKAVIQPTYPKGNHTLYYTTTMSSSEDGQLGLDSIKDQGEASLPPSPPHIGNGNAYNPY 220
            |:.|....|:..|..                    |||::.:|:       ||
Mosquito   271 LLVWAISAAIGSPIV--------------------LGLNNTQDR-------SP------------ 296

  Fly   221 DPGFAPIDGSAEIRIAAIDSTSTSTTATTTTTASSSSTTETEMDLDLLNAPPQNRPQTISGSCPW 285
                                                         ||
Mosquito   297 ---------------------------------------------DL------------------ 298

  Fly   286 KCELTNDRGYVLYSALGSFYIPMFVMLFFYWRIYRAAVRTTRA-------------------INQ 331
             |...| ..:::||:|.|||||..:|:|.||.|::|.  .|||                   |.:
Mosquito   299 -CVFYN-TDFIVYSSLTSFYIPCIIMVFLYWNIFKAL--RTRAKKQRAARKPHLSEITAGGSIIE 359

  Fly   332 GFKTTK--------GSKGIGSRF--EEQRLTLRIHRGRGSNQQDSMHSNG----------STQST 376
            ....||        ||...||:.  :|:|.|   :...|||::|..::..          :.:||
Mosquito   360 NIAQTKRLAETQLDGSTRSGSKILPDEERPT---NTASGSNEEDDENAGSPDIDDCHVIVNDKST 421

  Fly   377 TTTLGTPSPERLSK-YATRRLHHHDKIKISVSYPSSENISELAGHGDVGHERRQSGNALFAVH-- 438
            ...|.|...|..:| ::|.......:|..:...||..|     |:.|.|:......:|| ||:
Mosquito   422 EFMLATVVEEAGNKSFSTSTFSVVAQIATTQQVPSDPN-----GNHDSGYAPSSIADAL-AVNAT 480

  Fly   439 ---------------------YNGTNGRESTESQLYRQQQQHGVASSCYLQVGKGLPELARRQSN 482
                                 .||:..:|::.:.......:.||..:..|...........|.|:
Mosquito   481 PPESLNVTATVIVNKSATIRSRNGSPRKEASVTLKPLSLVRCGVQQALTLNRNDSTLSTNSRDSS 545

  Fly   483 TSEAGGSGHSR----PANKKMGRRNIKAQVKRFRMETKAAKTLAIIVGMFIFCWCPFFTMYIIRP 543
            ..:...:..||    ..||...::..|:..|:   |.||.|||||::|:|:|||.||||..|:..
Mosquito   546 RKDKKNTQASRFTIYKVNKASKKKREKSSAKK---ERKATKTLAIVLGVFLFCWVPFFTCNIMDA 607

  Fly   544 FC----QDCVDPL-LFSVLFWLGYCNSAVNPMIYALFSKDFRFAFKRII 587
            .|    :||...: :|::..||||.||.|||:||.:|:.:||.|||:|:
Mosquito   608 MCAKLDKDCRPGVTIFNLTTWLGYMNSFVNPVIYTIFNPEFRKAFKKIM 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oamb	NP_001262774.1	7tmA_Octopamine_R	21..583	CDD:320191	162/628 (26%)
		TM helix 1	22..48	CDD:320191	9/21 (43%)
		TM helix 2	55..81	CDD:320191	15/25 (60%)
		TM helix 3	93..123	CDD:320191	16/29 (55%)
		TM helix 4	135..158	CDD:320191	2/22 (9%)
		TM helix 5	292..321	CDD:320191	13/28 (46%)
		TM helix 6	512..542	CDD:320191	18/29 (62%)
		TM helix 7	551..576	CDD:320191	12/25 (48%)
Dop2R	XP_061499915.1	None