Protein Alignment Oamb and Adra2c

DIOPT Version :9

• Sequence 1: NP_001262774.1
• Gene: Oamb / 43982
• FlyBaseID: FBgn0024944
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_031444.2
• Gene: Adra2c / 11553
• MGIID: 87936
• Length: 458
• Species: Mus musculus
• Alignment Length: 594
• Identity: 159/594 - (26%)
• Similarity: 234/594 - (39%)
• Gaps: 201/594 - (33%)

  Fly    15 WTEPANLIS-------LAVLEFINVLVIGGNCLVIAAVFCSNKLRSVTNFFIVNLAVADLLVGLA 72
            |..|....|       .||:.|:.|..:.||.||:.||..|..||:..|.|:|:||.||:||...
Mouse    39 WVPPPGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATL 103

  Fly    73 VLPFSATWEVFKVWIFGDLWCRIWLAVDVWMCTASILNLCAISLDRYVAVTRPVTYPSIMSTKKA 137
            |:|||...|:...|.||.:||.::||:||..||:||::|||||||||.:||:.|.|....:.::.
Mouse   104 VMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRV 168

  Fly   138 KSLIAGIWVLSFFICFPPLVGWKDQKAVIQPTYPKGNHTLYYTTTMSSSEDGQLGLDSIKDQGEA 202
            |:.|..:|::|..|.|||||.                   :|...
Mouse   169 KATIVAVWLISAVISFPPLVS-------------------FYRRP-------------------- 194

  Fly   203 SLPPSPPHIGNGNAYNPYDPGFAPIDGSAEIRIAAIDSTSTSTTATTTTTASSSSTTETEMDLDL 267
                      :|.||
Mouse   195 ----------DGAAY-------------------------------------------------- 199

  Fly   268 LNAPPQNRPQTISGSCPWKCELTNDRGYVLYSALGSFYIPMFVMLFFYWRIYRAAVRTTRAINQG 332
                    ||         |.|.::..|:|.|.:|||:.|..:|...|.||||.|...||.:::
Mouse   200 --------PQ---------CGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSE- 246

  Fly   333 FKTTKGSKGIGSRFEEQRLTLRIHRGRGSNQQDSMHSNGSTQSTTTTLGTPSPERLSKYATRRLH 397
               .:|..|                           .:|::.:|...||..:.|.         .
Mouse   247 ---KRGPAG---------------------------PDGASPTTENGLGKAAGEN---------G 272

  Fly   398 HHDKIKISVSYPSSENISELAGHGDVGHERRQSGNALFAVHYNGTNGRESTESQLYRQQQQHGVA 462
            |....:..|. |...:.:          |||:...||    ..|...||..|...       |.|
Mouse   273 HCAPPRTEVE-PDESSAA----------ERRRRRGAL----RRGGRRREGAEGDT-------GSA 315

  Fly   463 SSCYLQVGKGL-PELARRQSNTSEAGGSGHSRPANKKM-----GRRNIKAQVKRFRM----ETKA 517
            ..    .|.|| .|...|.::.|...|...||.:::.:     .||..::.|.|.::    |.:.
Mouse   316 DG----PGPGLAAEQGARTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRF 376

  Fly   518 AKTLAIIVGMFIFCWCPFFTMYIIRPFCQD-CVDP-LLFSVLFWLGYCNSAVNPMIYALFSKDFR 580
            ...||:::|:|:.||.|||..|.:...|:: |..| .||...||:|||||::||:||.:|::|||
Mouse   377 TFVLAVVMGVFVLCWFPFFFSYSLYGICREACQLPEPLFKFFFWIGYCNSSLNPVIYTVFNQDFR 441

  Fly   581 FAFKRIICR 589
            .:||.|:.|
Mouse   442 RSFKHILFR 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oamb	NP_001262774.1	7tm_4	29..>154	CDD:304433	56/124 (45%)
		7tm_1	37..>181	CDD:278431	60/143 (42%)
Adra2c	NP_031444.2	7tmA_alpha2C_AR	60..444	CDD:320446	150/565 (27%)
		TM helix 2	86..112	CDD:320446	13/25 (52%)
		TM helix 3	124..154	CDD:320446	18/29 (62%)
		TM helix 4	166..189	CDD:320446	9/22 (41%)
		TM helix 5	207..236	CDD:320446	12/28 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	245..343		28/163 (17%)
		TM helix 6	371..401	CDD:320446	11/29 (38%)
		TM helix 7	412..437	CDD:320446	13/24 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.870