Protein Alignment Oamb and adra1a

DIOPT Version :9

• Sequence 1: NP_001262774.1
• Gene: Oamb / 43982
• FlyBaseID: FBgn0024944
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: XP_002933012.2
• Gene: adra1a / 100492776
• XenbaseID: XB-GENE-6048410
• Length: 489
• Species: Xenopus tropicalis
• Alignment Length: 606
• Identity: 159/606 - (26%)
• Similarity: 223/606 - (36%)
• Gaps: 282/606 - (46%)

  Fly    16 TEPANLISLAVLEFINVLVIG------------GNCLVIAAVFCSNKLRSVTNFFIVNLAVADLL 68
            |.|...|:::     ..:|:|            ||.|||.:|.|...|::||::||.||||||||
 Frog    39 THPGATINIS-----KAIVVGVIFGVFITFGVLGNILVILSVACHRHLQTVTHYFIANLAVADLL 98

  Fly    69 VGLAVLPFSATWEVFKVWIFGDLWCRIWLAVDVWMCTASILNLCAISLDRYVAVTRPVTYPSIMS 133
            :...|||||||:|:...|:||.::|.||.||||..|||||::|||||:|||:.|:.|:.|||||:
 Frog    99 LMSMVLPFSATFEIQGYWLFGRIFCNIWAAVDVLCCTASIMSLCAISIDRYIGVSYPLRYPSIMT 163

  Fly   134 TKKAKSLIAGIWVLSFFICFPPLVGWKDQKAVIQPTYPKGNHTLYYTTTMSSSEDGQLGLDSIKD 198
            .|:....:..|||||..|...||.|||      ||                :.||.::
 Frog   164 EKRGVLALLCIWVLSLVISIGPLFGWK------QP----------------APEDDKI------- 199

  Fly   199 QGEASLPPSPPHIGNGNAYNPYDPGFAPIDGSAEIRIAAIDSTSTSTTATTTTTASSSSTTETEM 263
                                                                             
 Frog   200 ----------------------------------------------------------------- 199

  Fly   264 DLDLLNAPPQNRPQTISGSCPWKCELTNDRGYVLYSALGSFYIPMFVMLFFYWRIYRAAVRTTRA 328
                                   ||:|.:.||.|:||.||||:|:.::|..|:|:|..|.|.::.
 Frog   200 -----------------------CEITKEPGYALFSAFGSFYLPLSIILVMYFRVYIVAKRESKV 241

  Fly   329 INQGFKTTKGSKGIGSRFEEQRLTLRIHRGRGSNQQDSMHSNGSTQSTTTTLGTPSPERLSKYAT 393
            :..|.|..|.        :.:.:||||||      :.:..|.|||.|:
 Frog   242 LTSGMKLEKS--------DSEEVTLRIHR------KSTPESIGSTSSS----------------- 275

  Fly   394 RRLHHHDKIKISVSYPSSENISELAGHGDVGHERRQSGNALFAVHYNGTNGRESTESQLYRQQQQ 458
                                                                        :|:.|
 Frog   276 ------------------------------------------------------------KQKTQ 280

  Fly   459 HGVASSCYLQVGKGLPELARRQSNTSEAGGSGHSRPANKKMGRRNIKAQVKRFRMETKAAKTLAI 523
            ..|                                             ::.:|..|.||||||.|
 Frog   281 FSV---------------------------------------------RLLKFSREKKAAKTLGI 300

  Fly   524 IVGMFIFCWCPFFTMYIIRPFCQDCVDP------LLFSVLFWLGYCNSAVNPMIYALFSKDFRFA 582
            :||.|:.||.|||   ::.|.  ..:.|      .:|.:.|||||.||.:||:||...|.:||.|
 Frog   301 VVGCFVLCWLPFF---LVMPI--GSIYPPANSSDTIFKITFWLGYFNSCINPVIYPCSSPEFRKA 360

  Fly   583 FKRII-CRCFCSRQSVSLKSS 602
            |:.|: .||...||:.|..||
 Frog   361 FQNILHARCSHRRQAASKYSS 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oamb	NP_001262774.1	7tm_4	29..>154	CDD:304433	67/136 (49%)
		7tm_1	37..>181	CDD:278431	72/143 (50%)
adra1a	XP_002933012.2	7tmA_alpha1A_AR	51..361	CDD:320448	146/567 (26%)
		TM helix 1	52..78	CDD:320448	8/25 (32%)
		TM helix 2	85..111	CDD:320448	18/25 (72%)
		TM helix 3	123..153	CDD:320448	20/29 (69%)
		TM helix 4	165..188	CDD:320448	9/22 (41%)
		TM helix 5	205..234	CDD:320448	14/28 (50%)
		TM helix 6	289..319	CDD:320448	17/34 (50%)
		TM helix 7	329..354	CDD:320448	12/24 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H68078
Inparanoid	1	1.050	298	1.000	Inparanoid score	I2667
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1095345at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.970