Protein Alignment Oamb and taar1

DIOPT Version :10

• Sequence 1: NP_001262774.1
• Gene: Oamb / 43982
• FlyBaseID: FBgn0024944
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: XP_002935857.1
• Gene: taar1 / 100487786
• XenbaseID: XB-GENE-961114
• Length: 339
• Species: Xenopus tropicalis
• Alignment Length: 584
• Identity: 111/584 - (19%)
• Similarity: 167/584 - (28%)
• Gaps: 272/584 - (46%)

  Fly     7 EDLIKSVKWTEPANLISLAVLEFINVLVIG---GNCLVIAAVFCSNKLRSVTNFFIVNLAVADLL 68
            |.:.:|.:....:|.|.:.:..|:...::.   ||..||.::....:|.:.||:.|::::..|.|
 Frog     8 ESINRSCEKNGWSNNIRIPMYVFMVSTILATVVGNLAVIISIAHFKQLHTPTNYLILSMSTVDFL 72

  Fly    69 VGLAVLPFSATWEVFKVWIFGDLWCRIWLAVDVWMCTASILNLCAISLDRYVAVTRPVTYPSIMS 133
            :|..|:|:|....|...|.||||:|::..:.|:.:.|:||.:|..||:|||.||..|:.|.:.|:
 Frog    73 LGSCVMPYSMVRSVENCWYFGDLFCKVHTSTDIMLSTSSIFHLSFISVDRYFAVCDPLRYKTKMN 137

  Fly   134 TKKAKSLIAGIWVLSFFICFPPLVGWKDQKAVIQPTYPKGNHTLYYTTTMSSSEDGQLGLDSIKD 198
            ......:|...||:.....|         ..|......||..:.||...
 Frog   138 VFSVSLMIVTSWVVPTIFAF---------TMVFLELNIKGTESYYYNQV---------------- 177

  Fly   199 QGEASLPPSPPHIGNGNAYNPYDPGFAPIDGSAEIRIAAIDSTSTSTTATTTTTASSSSTTETEM 263
                                                                             
 Frog   178 ----------------------------------------------------------------- 177

  Fly   264 DLDLLNAPPQNRPQTISGSCPWKCELTNDRGYVLYSALGSFYIPMFVMLFFYWRIYRAAVRTTRA 328
                              ||...|.:...:...|.:::.|||||.||||..|.:||..|.|..|:
 Frog   178 ------------------SCFGGCAVFFSQTSGLVASMVSFYIPGFVMLCVYGKIYVIARRQARS 224

  Fly   329 INQGFKTTKGSKGIGSRFEEQRLTLRIHRGRGSNQQDSMHSNGSTQSTTTTLGTPSPERLSKYAT 393
            |..                            .:||....          .|||.
 Frog   225 IKD----------------------------SANQMPFQ----------ITLGV----------- 240

  Fly   394 RRLHHHDKIKISVSYPSSENISELAGHGDVGHERRQSGNALFAVHYNGTNGRESTESQLYRQQQQ 458
                                                                           .|
 Frog   241 ---------------------------------------------------------------NQ 242

  Fly   459 HGVASSCYLQVGKGLPELARRQSNTSEAGGSGHSRPANKKMGRRNIKAQVKRFRMETKAAKTLAI 523
            |                                                |.|.| :.||||||.|
 Frog   243 H------------------------------------------------VSRSR-DRKAAKTLGI 258

  Fly   524 IVGMFIFCWCPFFTMYIIRPFCQDCVDPLLFSVLFWLGYCNSAVNPMIYALFSKDFRFAFKRII 587
            |:|:|:.||.|||.......|....:.|::.....|:||.||..|||:||.|...|:.|.:.|:
 Frog   259 IMGVFLICWTPFFFCTATDGFINYVIPPIVIDAFVWIGYLNSTFNPMVYAFFYLWFQRALRMIL 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oamb	NP_001262774.1	7tmA_Octopamine_R	21..583	CDD:320191	106/564 (19%)
		TM helix 1	22..48	CDD:320191	6/28 (21%)
		TM helix 2	55..81	CDD:320191	9/25 (36%)
		TM helix 3	93..123	CDD:320191	12/29 (41%)
		TM helix 4	135..158	CDD:320191	4/22 (18%)
		TM helix 5	292..321	CDD:320191	13/28 (46%)
		TM helix 6	512..542	CDD:320191	16/29 (55%)
		TM helix 7	551..576	CDD:320191	11/24 (46%)
taar1	XP_002935857.1	7tmA_TAAR1	25..318	CDD:320438	105/561 (19%)
		TM helix 1	26..52	CDD:320438	5/25 (20%)
		TM helix 2	59..85	CDD:320438	9/25 (36%)
		TM helix 3	97..127	CDD:320438	12/29 (41%)
		TM helix 4	139..162	CDD:320438	5/31 (16%)
		TM helix 5	188..217	CDD:320438	13/28 (46%)
		TM helix 6	247..277	CDD:320438	16/30 (53%)
		TM helix 7	286..311	CDD:320438	11/24 (46%)