Protein Alignment Lip2 and LIPF

DIOPT Version :9

• Sequence 1: NP_524667.1
• Gene: Lip2 / 43980
• FlyBaseID: FBgn0024740
• Length: 413
• Species: Drosophila melanogaster
• Sequence 2: NP_001185758.1
• Gene: LIPF / 8513
• HGNCID: 6622
• Length: 408
• Species: Homo sapiens
• Alignment Length: 418
• Identity: 124/418 - (29%)
• Similarity: 190/418 - (45%)
• Gaps: 94/418 - (22%)

  Fly    24 HSSPPESRYKWTTMDWLEAQNVS---------HEVHNVTTADGYQLQLQRLP-------RLGAKP 72
            |...||     .||      |:|         :|.:.|.|.|||.|::.|:|       ..|.:|
Human    35 HPGSPE-----VTM------NISQMITYWGYPNEEYEVVTEDGYILEVNRIPYGKKNSGNTGQRP 88

  Fly    73 VL-LVHGLLGSSLGWVCMGPERSLAFQLHHREYDVWLANLRGVSPYGRQHIDLTDVMVEFWRFSF 136
            |: |.||||.|:..|:...|..||||.|....|||||.|.|| :.:.|:::..:...||||.|||
Human    89 VVFLQHGLLASATNWISNLPNNSLAFILADAGYDVWLGNSRG-NTWARRNLYYSPDSVEFWAFSF 152

  Fly   137 HEHGAYDLPAIIDHMAKVTGGEQLASRGGPGQDEEQIHHQVVLIGHSQAFNAFLVLCAVHPRFNQ 201
            .|...|||||.||.:.|.||             ::|:|:    :||||......:..:.:|...:
Human   153 DEMAKYDLPATIDFIVKKTG-------------QKQLHY----VGHSQGTTIGFIAFSTNPSLAK 200

  Fly   202 RIQLIQALAPLARLHRQVRFDSFQVRRLMKFIKKRQKAYKF----EIFPPGYF------RKVCQA 256
            ||:...||||:|    .|::....:.:| :|:.  |..:||    :||.|..|      .:||..
Human   201 RIKTFYALAPVA----TVKYTKSLINKL-RFVP--QSLFKFIFGDKIFYPHNFFDQFLATEVCSR 258

  Fly   257 K--RDLCEYYAKQLVGSAQNNKKLLEAFNYE----YLLQ---GGSPREIKHLQQIWKSGDFISYD 312
            :  ..||......:.|....|      ||..    ||..   |.|.:.:.|..|..|||.|.:||
Human   259 EMLNLLCSNALFIICGFDSKN------FNTSRLDVYLSHNPAGTSVQNMFHWTQAVKSGKFQAYD 317

  Fly   313 FGT-AENLQVYHSVEALSYNISQITVPIILYFGETDAIATPEGVHAIYARMLRSV--KSVRRINS 374
            :|: .:|...|...:...||::.:.|||.::.|..|.:|.|:.|..:..::...:  |.:
Human   318 WGSPVQNRMHYDQSQPPYYNVTAMNVPIAVWNGGKDLLADPQDVGLLLPKLPNLIYHKEI----- 377

  Fly   375 KKFNHLDFL--------ISGDVKSLVND 394
            ..:|||||:        :..|:.|::::
Human   378 PFYNHLDFIWAMDAPQEVYNDIVSMISE 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lip2	NP_524667.1	PLN02872	24..407	CDD:215470	124/418 (30%)
		Abhydro_lipase	48..90	CDD:282003	19/49 (39%)
LIPF	NP_001185758.1	PLN02872	14..400	CDD:215470	123/411 (30%)
		Abhydro_lipase	45..107	CDD:282003	20/61 (33%)
		Abhydrolase_5	88..>211	CDD:289465	54/140 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141809
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.860