Protein Alignment Lip2 and YEH2

DIOPT Version :10

• Sequence 1: NP_524667.1
• Gene: Lip2 / 43980
• FlyBaseID: FBgn0024740
• Length: 413
• Species: Drosophila melanogaster
• Sequence 2: NP_013120.1
• Gene: YEH2 / 850707
• SGDID: S000004010
• Length: 538
• Species: Saccharomyces cerevisiae
• Alignment Length: 439
• Identity: 99/439 - (22%)
• Similarity: 158/439 - (35%)
• Gaps: 120/439 - (27%)

  Fly    28 PESRYKWTTMDWLEAQNVSHEVHNVTTADGYQLQL----QRL----PRLGAKPVLLVHGLLGSSL 84
            |:.:|      :.:...:..|...|.|.||:.:.|    .||    ..:..:|:||:|||| .|.
Yeast   148 PDLKY------YYKEYGIDIEEFEVETDDGFIIDLWHFKSRLNDGVEEVKREPILLLHGLL-QSC 205

  Fly    85 GWVCMGPERSLAFQLHHREYDVWLANLR-------GVSPYGRQHIDLTDVMVEFWRFSFHEHGAY 142
            |.......:|||:.|:...:||||.|.|       .:...|..|       .:.|.:..|:...|
Yeast   206 GAFASSGRKSLAYFLYESGFDVWLGNNRCGLNAKWNMKKLGNDH-------SKKWDWDMHQMVQY 263

  Fly   143 DLPAIIDHMAKVTGGEQLASRGGPGQDEEQIHHQVVLIGHSQ-AFNAFLVLCAVHPRFNQRIQLI 206
            ||.|:|:::...||..:|:                 |:.||| ....|:.|......:....:|:
Yeast   264 DLKALINYVLDSTGYAKLS-----------------LVAHSQGTTQGFMGLVNGEKLYASDFKLV 311

  Fly   207 Q------ALAPLARLHRQVRFDSFQVRRLMKFIKKRQKAYKFEIFPPGYFRKVCQAKRDLCEYYA 265
            .      ||||.......:...:| ||.:.|.|..           |.||.:  ::...|.....
Yeast   312 DKLENFVALAPAVYPGPLLDEKAF-VRLMAKGIDS-----------PWYFGR--RSFIPLMMTMR 362

  Fly   266 KQLVGSAQNNKKLLEAFNY---EYLLQGG---------------SPREIK-HLQQIW-------- 303
            |.:||:     |:....:|   .||....               ||..|. .|.|.|
Yeast   363 KLMVGT-----KIFSFLSYIMFNYLFDWNDVLWDRVLRDRNFLFSPVHISVKLMQWWLSPLPNKL 422

  Fly   304 ---KSGDFISYD----FGTAENLQVYHSVEALSYN---------ISQITVPIILYFGETDAIATP 352
               |..:.|..|    |..|:|..  .|...|..|         .|:....||::..:.|.:.
Yeast   423 SFKKGAEKIFPDKKTWFPIAKNDD--DSGNNLDNNKLHLNPKRQNSEEFPHIIMFIPKQDRLV-- 483

  Fly   353 EGVHAIYARMLRSVKSVRRI-NSKKFNHLDFLISGDVKSLVNDKLIEHM 400
            :|...|...:.....:|.:| ...:::|||.|.:.||...:...:||::
Yeast   484 DGERLINHFINHEANAVYKIWYIDEYSHLDVLWAHDVIDRIGKPMIENL 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lip2	NP_524667.1	PLN02872	24..407	CDD:215470	99/439 (23%)
YEH2	NP_013120.1	PLN02872	163..>298	CDD:215470	43/159 (27%)
		alpha/beta hydrolases	194..435	CDD:473884	66/284 (23%)