Protein Alignment Lip2 and LIPN

DIOPT Version :10

• Sequence 1: NP_524667.1
• Gene: Lip2 / 43980
• FlyBaseID: FBgn0024740
• Length: 413
• Species: Drosophila melanogaster
• Sequence 2: NP_001095939.1
• Gene: LIPN / 643418
• HGNCID: 23452
• Length: 398
• Species: Homo sapiens
• Alignment Length: 397
• Identity: 106/397 - (26%)
• Similarity: 168/397 - (42%)
• Gaps: 64/397 - (16%)

  Fly    39 WLEAQNV------SHEVHNVTTADGYQLQLQRLP-------RLGAKPVL-LVHGLLGSSLGWVCM 89
            |:....:      ..|.:.|||.|||.|.:.|:|       ..|.:||: :.|.|...:..|:..
Human    33 WMNTSEIIIYNGYPSEEYEVTTEDGYILLVNRIPYGRTHARSTGPRPVVYMQHALFADNAYWLEN 97

  Fly    90 GPERSLAFQLHHREYDVWLANLRGVSPYGRQHIDLTDVMVEFWRFSFHEHGAYDLPAIIDHMAKV 154
            ....||.|.|....||||:.|.|| :.:.|:|..|::...:||.|||.|...||||.:||.:...
Human    98 YANGSLGFLLADAGYDVWMGNSRG-NTWSRRHKTLSETDEKFWAFSFDEMAKYDLPGVIDFIVNK 161

  Fly   155 TGGEQLASRGGPGQDEEQIHHQVVLIGHSQAFNAFLVLCAVHPRFNQRIQLIQALAPLARLHRQV 219
            ||.|:|                 ..||||.......|..:..|...|||::..||.|      .:
Human   162 TGQEKL-----------------YFIGHSLGTTIGFVAFSTMPELAQRIKMNFALGP------TI 203

  Fly   220 RFDSFQVRRLMKFIKKRQKAYKFEIFPPGYF----------RKVCQAK--RDLCEYYAKQLVGSA 272
            .| .:......:|........|......|:|          .|:|..|  ..:|..:.....||
Human   204 SF-KYPTGIFTRFFLLPNSIIKAVFGTKGFFLEDKKTKIASTKICNNKILWLICSEFMSLWAGS- 266

  Fly   273 QNNKKLLEAFNYEYLLQ----GGSPREIKHLQQIWKSGDFISYDFGT-AENLQVYHSVEALSYNI 332
              |||.:.....:..:.    |.|...|.|::|::.|.:|.:||:|. |:|::.|:......|::
Human   267 --NKKNMNQSRMDVYMSHAPTGSSVHNILHIKQLYHSDEFRAYDWGNDADNMKHYNQSHPPIYDL 329

  Fly   333 SQITVPIILYFGETDAIATPEGVHAIYARMLRSVKSVRRIN-SKKFNHLDFLISGDVKSLVNDKL 396
            :.:.||..::.|..|.:.||:.|    ||:|..:||:.... ...:||.||:...|....:..::
Human   330 TAMKVPTAIWAGGHDVLVTPQDV----ARILPQIKSLHYFKLLPDWNHFDFVWGLDAPQRMYSEI 390

  Fly   397 IEHMEQF 403
            |..|:.:
Human   391 IALMKAY 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lip2	NP_524667.1	PLN02872	24..407	CDD:215470	106/397 (27%)
LIPN	NP_001095939.1	PLN02872	37..396	CDD:215470	105/390 (27%)