DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lip2 and CG11608

DIOPT Version :9

Sequence 1:	NP_524667.1	Gene:	Lip2 / 43980	FlyBaseID:	FBgn0024740	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_650218.3	Gene:	CG11608 / 41556	FlyBaseID:	FBgn0038069	Length:	430	Species:	Drosophila melanogaster

Alignment Length:	388	Identity:	111/388 - (28%)
Similarity:	187/388 - (48%)	Gaps:	47/388 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 TTMDWLEAQNVSHEVHNVTTADGYQLQLQRLP--RLGA----KPVLLV-HGLLGSSLGWVCMGPE 92
            |.:|.:.:.|...:.|.|.|.|||.|.:.|:|  :|.|    |||:|: ||:.||:..|:..||.
  Fly    47 TAVDIISSHNYPVQTHTVVTRDGYILSVFRIPSSQLCASSEPKPVVLINHGMTGSADSWLLTGPR 111

  Fly    93 RSLAFQLHHREYDVWLANLRGVSPYGRQHIDLTDVMVEFWRFSFHEHGAYDLPAIIDHMAKVTGG 157
            ..|.|.|....|||||.|.|| :.|.|:|:.|...:::|||||:||.|..||||.:||:
  Fly   112 NGLPFLLADACYDVWLINCRG-TRYSRKHLKLKAWLLQFWRFSWHEIGMEDLPATVDHI------ 169

  Fly   158 EQLASRGGPGQDEEQIHHQVVLIGHSQAFNAFLVLCAVHPRFNQRIQLIQALAPLARLHRQVRFD 222
              |||     .....:|:    :||||...:.||:.::.|.:|:||:....|||...|...:...
  Fly   170 --LAS-----TKRNSLHY----VGHSQGCTSMLVMLSMRPEYNKRIRTTILLAPPVFLKHSLSMG 223

  Fly   223 SFQVRRLMKFIKKRQKAYKFEIFPPGYFRKVCQAKRDLCEYYAKQLVGSA---QNNKKLLEAFNY 284
            ...::.|...:.      ..|:.|  :.:.:..|...:|:....:.|.:|   ..|.::.:..|.
  Fly   224 HKIMKPLFNLLP------DIELLP--HHKMLNSAVSAICKILGVKDVCTALYLLTNGRVSQHMNR 280

  Fly   285 EYLLQ-------GGSPREIKHLQQIWKSGDFISYDFGTAENLQVYHSVEALSYNISQIT--VPII 340
            ..:..       |.|.|:.:|..|:..||.|..||||...|..:|.......|.:..:.  ..|.
  Fly   281 TLIPMLIATHPAGISSRQPRHFFQLKDSGRFRQYDFGFGMNYLIYRQNTPPEYPLEMVRPHSAIH 345

  Fly   341 LYFGETDAIATPEGVHAIYARMLRSVKSVRRINSKKFNHLDFLISGDVKSLVNDKLIEHMEQF 403
            :::.:.|...:|..|..:.:::..:|.  ..|..:.:||:|||::.::..|:|:.:|:.::.|
  Fly   346 IFYSDDDGTISPRDVLTLASKLPYAVP--HHITDETWNHMDFLLANNINELINNPVIKIIKTF 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lip2	NP_524667.1	PLN02872	24..407	CDD:215470	111/388 (29%)
Lip2	NP_524667.1	Abhydro_lipase	48..90	CDD:282003	20/48 (42%)
CG11608	NP_650218.3	PLN02872	39..405	CDD:215470	110/385 (29%)
		Abhydro_lipase	49..109	CDD:282003	22/59 (37%)
		Abhydrolase_5	91..>212	CDD:289465	53/138 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439448
Domainoid	1	1.000	108	1.000	Domainoid score	I1418
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		otm46497
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
	9	8.850