DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lip2 and CG11406

DIOPT Version :9

Sequence 1:	NP_524667.1	Gene:	Lip2 / 43980	FlyBaseID:	FBgn0024740	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_001014548.1	Gene:	CG11406 / 37877	FlyBaseID:	FBgn0034990	Length:	396	Species:	Drosophila melanogaster

Alignment Length:	388	Identity:	117/388 - (30%)
Similarity:	180/388 - (46%)	Gaps:	52/388 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 LEAQNVSHEVHNVTTADGYQLQLQRLPR-------LGAKPVLLVHGLLGSSLGWVCMGPERSLAF 97
            ::.|.:..:||.:.|||||:|.|.|:|.       ...:|.||:||||||:..:|..|..||||.
  Fly    28 VQRQQLQCQVHRIETADGYRLSLHRIPAPQNRWCPQQLRPFLLMHGLLGSAGDFVSGGRGRSLAL 92

  Fly    98 QLHHREYDVWLANLRGVSPYGRQHIDLTDVMVEFWRFSFHEHGAYDLPAIIDHMAKVTGGEQLAS 162
            :||.|.:||||||.||.: :.|.|..|......|||||:||.|.||||||:|::...|
  Fly    93 ELHARCFDVWLANARGTT-HSRGHRTLQTSDARFWRFSWHEIGIYDLPAIVDYVLART------- 149

  Fly   163 RGGPGQDEEQIHHQVVLIGHSQAFNAFLVLCAVHPRFNQRIQLIQALAPLARLH-------RQVR 220
                  :..|:|:    :||||.....|||.:..|.:|.|......|||:|.|.       |.:.
  Fly   150 ------NRRQLHY----VGHSQGTTVLLVLLSQRPEYNARFANAALLAPVAFLQHLSSPPLRLLA 204

  Fly   221 FDSFQVRRLMKFIKKRQKAYKFEIFPPGYFRKV-----CQAKRD---LCEYYAKQLVGSAQN--N 275
            .||.....|:      .|....|:.|.....:|     |.|.|.   ||..:....||.:..  :
  Fly   205 SDSSMATLLL------NKLGLHELLPASALTQVGGQFFCTASRPTYALCTLFTSVYVGFSDYPLD 263

  Fly   276 KKLLEAFNYEYLLQGGSPREIKHLQQIWKSGDFISYDFGTAE-NLQVYHSVEALSYNISQITVPI 339
            :.:|... .|....|.|..:::|..|:..||.|..||:.:.. |...|......||.::.:.:.:
  Fly   264 RSILPRI-LETTPAGISRGQLQHFGQLINSGKFQQYDYRSPRLNTLRYGRTTPPSYQLANVRLQL 327

  Fly   340 ILYFGETDAIATPEGVHAIYARMLRSVKSVRRINSKKFNHLDFLISGDVKSLVNDKLIEHMEQ 402
            .::.|..|.:::...|..:...:..||..:.::..  :||:|||.:.....:|..::|:...|
  Fly   328 QIFHGSRDTLSSLADVQRLVRELRNSVTQMYQVPG--YNHIDFLFASSAPQVVFQRIIQQAWQ 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lip2	NP_524667.1	PLN02872	24..407	CDD:215470	117/388 (30%)
Lip2	NP_524667.1	Abhydro_lipase	48..90	CDD:282003	21/48 (44%)
CG11406	NP_001014548.1	Abhydro_lipase	28..85	CDD:282003	22/56 (39%)
		Abhydrolase_1	67..371	CDD:278959	102/330 (31%)
		Abhydrolase_5	67..>203	CDD:289465	63/153 (41%)
		Abhydrolase_5	<315..365	CDD:289465	7/51 (14%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439438
Domainoid	1	1.000	108	1.000	Domainoid score	I1418
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		otm46497
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
	9	8.850