DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lip2 and CG3635

DIOPT Version :9

Sequence 1:	NP_524667.1	Gene:	Lip2 / 43980	FlyBaseID:	FBgn0024740	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_610138.4	Gene:	CG3635 / 35447	FlyBaseID:	FBgn0032981	Length:	425	Species:	Drosophila melanogaster

Alignment Length:	391	Identity:	116/391 - (29%)
Similarity:	183/391 - (46%)	Gaps:	62/391 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 NVSHEVHNVTTADGYQLQLQRLP---------RLGAKPVL-LVHGLLGSSLGWVCMGPERSLAFQ 98
            |...|.|.|.|.|.|.|.:.|:|         |.|.:.|: |.||:|.:|..|:..|||.|||:.
  Fly    59 NYPVEEHTVITHDDYILTIYRIPSSPNRSHLNRAGRRAVVFLQHGILSASDDWIINGPEASLAYM 123

  Fly    99 LHHREYDVWLANLRGVSPYGRQHIDLTDVMVEFWRFSFHEHGAYDLPAIIDH-MAKVTGGEQLAS 162
            |....|||||.|.|| :.|.|||..:.....:|||||:||.|.|||.|::|: :||
  Fly   124 LADAGYDVWLGNARG-NTYSRQHKHIHPDTSDFWRFSWHEIGVYDLAAMLDYALAK--------- 178

  Fly   163 RGGPGQDEEQIHHQVVLIGHSQAFNAFLVLCAVHPRFNQRIQLIQALAPLARLHRQVRFDSFQVR 227
                 .....:|    .:.|||...||.||.:..|.:|::::.:..|||:|    .:|..||.:.
  Fly   179 -----SQSSSLH----FVAHSQGTTAFFVLMSSLPLYNEKLRSVHLLAPIA----YMRDHSFILS 230

  Fly   228 RL----------MKFIKKRQKAYKFEIFPPGYFRK-VCQ---AKRDLCEYYAKQLV------GSA 272
            :|          :.::     ....|:.|....:| :|:   :...:..:....|:      |:.
  Fly   231 KLGGIFLGTPSFLSWV-----LGSMELLPITNLQKLICEHICSSSSMFNFLCSGLLDFIGGWGTR 290

  Fly   273 QNNKKLLEAFNYEYLLQGGSPREIKHLQQIWKSGDFISYDFGTAENLQVYHSVEALSYNISQITV 337
            ..|:.||......: ..|.|..::.|..|:::||||..||.|...|..:|......|||:..|..
  Fly   291 HLNQTLLPDVCATH-PAGASSSQVIHYLQLYRSGDFRQYDHGPELNEIIYQQPTPPSYNVQYIKS 354

  Fly   338 PIILYFGETDAIATPEGVHAIYARMLRSVKSVRRINSKKFNHLDFLISGDVKSLVNDKLIEHMEQ 402
            .:.:|:.|.|.::....|.  |...|.....:.||..:.:||.|||.|.:||.::|:|:|:.:.:
  Fly   355 CVDMYYSENDYMSAVGDVK--YLASLLPCAQLYRIPFRDWNHYDFLWSNNVKEVINNKIIQKIRK 417

  Fly   403 F 403
            :
  Fly   418 Y 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lip2	NP_524667.1	PLN02872	24..407	CDD:215470	116/391 (30%)
Lip2	NP_524667.1	Abhydro_lipase	48..90	CDD:282003	18/51 (35%)
CG3635	NP_610138.4	Abhydro_lipase	55..115	CDD:282003	19/55 (35%)
CG3635	NP_610138.4	Abhydrolase_1	97..399	CDD:278959	97/332 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439468
Domainoid	1	1.000	108	1.000	Domainoid score	I1418
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		otm46497
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
	9	8.850