DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lip2 and CG31091

DIOPT Version :9

Sequence 1:	NP_524667.1	Gene:	Lip2 / 43980	FlyBaseID:	FBgn0024740	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_001247307.1	Gene:	CG31091 / 318591	FlyBaseID:	FBgn0051091	Length:	424	Species:	Drosophila melanogaster

Alignment Length:	435	Identity:	115/435 - (26%)
Similarity:	185/435 - (42%)	Gaps:	67/435 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 IVCA-----IGRNAHSSP-----------------PESRYKWT----TMDWLEAQNVSHEVHNVT 53
            ::||     :|....|:|                 |::....|    |:.::|......|.|.||
  Fly     8 VICAFVGIFVGTVVQSAPFSNDPAEVPNFYELFNNPDAHLSLTNGPDTIHFIEEHGYPVERHYVT 72

  Fly    54 TADGYQLQLQRLP-------RLGAKPVLLV-HGLLGSSLGWVCMGPERSLAFQLHHREYDVWLAN 110
            |.|||.:.|.|:|       :...:|:..: |||..||..|..:||:..|.|.|....|||||.|
  Fly    73 TEDGYIISLFRIPYSHNIQNQQEKRPIAFIQHGLFASSDFWPSLGPDDGLPFLLSDAGYDVWLGN 137

  Fly   111 LRGVSPYGRQHIDLTDVMVEFWRFSFHEHGAYDLPAIIDHMAKVTGGEQLASRGGPGQDEEQIHH 175
            .|| :.|.:.|........:|||||:||.|.:|:.|.||:......          |||::.||:
  Fly   138 ARG-NRYSKNHTSRLTSHPDFWRFSWHEIGYFDIAAAIDYTLSTEN----------GQDQKGIHY 191

  Fly   176 QVVLIGHSQAFNAFLVLCAVHPRFNQRIQLIQALAPLARLHRQVRFDSFQVRRLMKFIKKR---- 236
                |||||......||.:..|.:|.:|:....|||:|.:.   ..|...|..|..::...
  Fly   192 ----IGHSQGTTVMFVLLSSRPEYNDKIKTAHMLAPVAFMD---HMDDVMVNTLSPYLGFNNIYS 249

  Fly   237 -----QKAYKFEIFPPGYFRKVCQAKR---DLCEYYAKQLVGSAQNNKKLLEAFNYEYLLQGGSP 293
                 |:......|.......||..:.   ..|....:......:.| ....|.....:..|.|.
  Fly   250 TLFCSQEFLPHNDFVLALMYSVCLPESIVYSFCSSSNETTTEEGRTN-STASALTSGVMPAGVST 313

  Fly   294 REIKHLQQIWKSGDFISYDFGTAENLQVYHSVEALSYNISQITVPIILYFGETDAIATPEGVHAI 358
            .:|.|..|..:||.|..:||||.:|::||.:.....|....||..:.|::.::|.:|..|.|..:
  Fly   314 DQILHYMQEHQSGHFRQFDFGTKKNMKVYGTEAPEDYPTELITAEMHLWYSDSDEMAAVEDVLRV 378

  Fly   359 YARMLRSVKSVRRINSKKFNHLDFLISGDVKSLVNDKLIEHMEQF 403
             |..|.: |.:..:....::|:||.::.:|:..:||.::..:.::
  Fly   379 -AETLPN-KVMHHMEDPLWDHMDFALNWEVRQYINDPIVAILNEY 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lip2	NP_524667.1	PLN02872	24..407	CDD:215470	112/421 (27%)
Lip2	NP_524667.1	Abhydro_lipase	48..90	CDD:282003	18/49 (37%)
CG31091	NP_001247307.1	PLN02872	42..416	CDD:215470	110/394 (28%)
		Abhydro_lipase	55..117	CDD:282003	20/61 (33%)
		Abhydrolase_5	104..>239	CDD:289465	54/152 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439528
Domainoid	1	1.000	108	1.000	Domainoid score	I1418
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		otm46497
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
	8	7.950