DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lip2 and Lipk

DIOPT Version :9

Sequence 1:	NP_524667.1	Gene:	Lip2 / 43980	FlyBaseID:	FBgn0024740	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	XP_017444545.1	Gene:	Lipk / 294094	RGDID:	1309724	Length:	402	Species:	Rattus norvegicus

Alignment Length:	391	Identity:	113/391 - (28%)
Similarity:	172/391 - (43%)	Gaps:	76/391 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 HEVHNVTTADGYQLQLQRLPR-----LGAKP---VLLVHGLLGSSLGWVCMGPERSLAFQLHHRE 103
            :|.|:|.|.|||.|...|:|.     ..|.|   |.|.|||:.|:..|:|..|..||||.|....
  Rat    49 YERHDVVTEDGYILGTYRIPHGKGCSRKAVPKAVVYLQHGLIASASNWICNLPNNSLAFLLADSG 113

  Fly   104 YDVWLANLRGVSPYGRQHIDLTDVMVEFWRFSFHEHGAYDLPAIIDHMAKVTGGEQLASRGGPGQ 168
            |||||.|.|| :.:.|:|:.|:....|:|.||..|...|||||.|:.:.:.:|.:||
  Rat   114 YDVWLGNSRG-NTWSRKHLRLSPKSPEYWAFSLDEMAKYDLPATINLILEKSGQKQL-------- 169

  Fly   169 DEEQIHHQVVLIGHSQAFNAFLVLCAVHPRFNQRIQLIQALAPLARLHRQVRFDSFQVRRLMKFI 233
                     ..:||||......:..:.:|...::|::..||||:.    .|::....:::|....
  Rat   170 ---------FYVGHSQGTTIAFIAFSTNPELAKKIRMFFALAPVV----TVKYTQSPMKKLTTLS 221

  Fly   234 KKRQKAYKFEIFPPGYF-----------RKVCQAK--RDLCEYYAKQLVG-SAQN-NKKLLEAFN 283
            :|..|.    :|....|           .|||..|  |.||..:...|.| ..|| |...|:.
  Rat   222 RKAVKI----LFGDKMFSTHTWLEQFIATKVCNRKLFRQLCSNFLFSLSGFDPQNLNMSRLDV-- 280

  Fly   284 YEYLLQ---GGSPREIKHLQQIWKSGDFISYDFGTA-ENLQVYHSVEALSYNISQITVPIILYFG 344
              |:.|   |.|.:.:.|..|...||...::|:|.. :|:..::.:....||||::.||..::.|
  Rat   281 --YMAQSPAGTSVQNMLHWAQAVNSGQLQAFDWGNPDQNMMHFNQLTPPVYNISKMRVPTAMWSG 343

  Fly   345 ETDAIA--------TPEGVHAIYARMLRSVKSVRRINSKKFNHLDFLISGDVKSLVNDKLIEHME 401
            ..|.:|        .|:..:.||.:.:           ..:||:||.:..|....|...||..||
  Rat   344 GRDVVADEKDTKNLLPKVANLIYYKEI-----------PHYNHMDFYLGQDAPQEVYRDLITMME 397

  Fly   402 Q 402
            :
  Rat   398 E 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lip2	NP_524667.1	PLN02872	24..407	CDD:215470	113/391 (29%)
Lip2	NP_524667.1	Abhydro_lipase	48..90	CDD:282003	20/49 (41%)
Lipk	XP_017444545.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335562
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.860