| Sequence 1: | NP_651960.2 | Gene: | trio / 43974 | FlyBaseID: | FBgn0024277 | Length: | 2263 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_013475.1 | Gene: | ROM2 / 851086 | SGDID: | S000004363 | Length: | 1356 | Species: | Saccharomyces cerevisiae |
| Alignment Length: | 1046 | Identity: | 192/1046 - (18%) |
|---|---|---|---|
| Similarity: | 378/1046 - (36%) | Gaps: | 294/1046 - (28%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1435 ESHGEIKEGLEVMLNVPKKANDAMHLSLLENCDVSVD--------KLG-EVVLQDAFQAWDTKQI 1490
Fly 1491 IRKGRERRVFLFELYLLFAKEV--------KESNVVKYQFKSKLMTTDMGITEHIEGDETKFAVW 1547
Fly 1548 TGRS-----------PMLSDCRIVLKATSLETKQIWVKK-------LREVMQETCFS-GTSLTLP 1593
Fly 1594 ----KSPAKHSG-SSQRSSRDLDEQLTENDHDRCSLASFGSGNTTDSDN---KLGNQEATWVVAD 1650
Fly 1651 YIATSGSNELSVSKGQQVEIVEPPTAGEPDFCLVRLNPQHDDAAVQEGLVPVSVLKPPPGSHKH- 1714
Fly 1715 ---GSGTAANAASSAGSQKSDMQDQSN-----RSKADALSSSTKR-RGFSGRNWLPLMNRKGTDK 1770
Fly 1771 PPSSKPLVKKPSEK---------NLRTPQKHAEELAEQQ-----------NQQPGASPATVLPSS 1815
Fly 1816 -----------------------------------QFPSSTQHPGGAGAGDYEPDEEVGLELPPP 1845
Fly 1846 MKPIQEPHLIANGPPAFAKDAKESSGNMASP--GKMDGNPLSEI--EEIVKTTTEQHESNS---- 1902
Fly 1903 -------RVDG---------------------------------------GGGVENASTNGHGRS 1921
Fly 1922 HDNNDESHTAVSDKAA----------ALKKRQCVFAELMSTEEAYVQDLHEIVNGYMTEINNTNS 1976
Fly 1977 DIPMPEDLKGGKMKLVFNNIKDIYEWHRDFFLRALRNCQKSP---ADLGPLIKRSATKFALYYTY 2038
Fly 2039 CSNKPLSEYIVSAHYQ---YF-----DSIRQKLGHRLDLSNLIIKPVQRITKYELLIKEIIKATE 2095
Fly 2096 GAGLYKEVPMLQEAYQQMKVVVKTVNDMMVVLRSLQD-FDGEITAQGSLLMQGPMNCVVDAAQ-- 2157
Fly 2158 -KHR-----------------ELQVFLFQQIIIFADIEKTKNQYASPIFKYRSHIQL------NH 2198
Fly 2199 MQ--MKELG---DC-----RFQIRSTDPKIPEMTIICQAASQE--------NYAGWRDMLNKILQ 2245
Fly 2246 QQNDLI 2251 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| trio | NP_651960.2 | SEC14 | 13..152 | CDD:214706 | |
| SPEC | 314..>468 | CDD:238103 | |||
| SPEC | 563..778 | CDD:238103 | |||
| SPEC | 782..997 | CDD:238103 | |||
| SPEC | 897..1119 | CDD:238103 | |||
| SPEC | 1125..1226 | CDD:197544 | |||
| RhoGEF | 1287..1456 | CDD:279015 | 6/20 (30%) | ||
| PH1_Kalirin_Trio_like | 1462..1584 | CDD:270060 | 25/156 (16%) | ||
| PH | 1495..1580 | CDD:278594 | 16/110 (15%) | ||
| SH3_Kalirin_1 | 1643..1707 | CDD:212786 | 6/63 (10%) | ||
| RhoGEF | 1945..2122 | CDD:279015 | 48/187 (26%) | ||
| PH2_Kalirin_Trio_p63RhoGEF | 2130..2260 | CDD:270061 | 32/167 (19%) | ||
| ROM2 | NP_013475.1 | ROM1 | 4..1356 | CDD:227709 | 192/1046 (18%) |
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 62 | 1.000 | Domainoid score | I2478 |
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R3601 |
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 2.030 | |||||