| Sequence 1: | NP_651960.2 | Gene: | trio / 43974 | FlyBaseID: | FBgn0024277 | Length: | 2263 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_062645.2 | Gene: | Net1 / 56349 | MGIID: | 1927138 | Length: | 595 | Species: | Mus musculus |
| Alignment Length: | 557 | Identity: | 114/557 - (20%) |
|---|---|---|---|
| Similarity: | 208/557 - (37%) | Gaps: | 126/557 - (22%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1227 KSLGMSQQQLLLGSDGNSSISS-SSGDRHSDPTLEAK---------LNSSNKENKEINEEKRKSA 1281
Fly 1282 RRKEFIMAELMQTERAYVNDLATCIKCFLEEFRAGKSVPSALIGQEDV--IFGNIKEIHHFHQKI 1344
Fly 1345 FLR--ELEKYETMPEDVGHCFVTWASKFDMYVHYCKNKPTSNNLLVQ--HGGSFFEELQRRLE-- 1403
Fly 1404 ----VDHPLPAYLIKPVQRITKYQLLLKDLLSCCEESHGEIKEGLEVMLNVPKKANDAMHLSLLE 1464
Fly 1465 N-CDVSVDKLGEVVLQDAFQAWDTKQII--------RKGRERRVFLFELYLLFAKEVKESNVVKY 1520
Fly 1521 Q-FKSKLMTTDMGITEHIEGDETKFAVWTGR------------------SPMLSDCRIVLKATSL 1566
Fly 1567 ETKQIWVKKLREVMQETCFSGTSLTLPKSPAKHSGSSQRSSRDLDEQLTENDHDRCSLASFGSGN 1631
Fly 1632 TTDSDNKLGNQEATWVVADYIATSGSNELSVSKGQQVEIVEPPTAGEPDFCLVRLNPQHDDAAVQ 1696
Fly 1697 EGLVPVSVLKPPPGSHKHGSGTAANAASSAGSQKSDM 1733 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| trio | NP_651960.2 | SEC14 | 13..152 | CDD:214706 | |
| SPEC | 314..>468 | CDD:238103 | |||
| SPEC | 563..778 | CDD:238103 | |||
| SPEC | 782..997 | CDD:238103 | |||
| SPEC | 897..1119 | CDD:238103 | |||
| SPEC | 1125..1226 | CDD:197544 | |||
| RhoGEF | 1287..1456 | CDD:279015 | 46/180 (26%) | ||
| PH1_Kalirin_Trio_like | 1462..1584 | CDD:270060 | 24/149 (16%) | ||
| PH | 1495..1580 | CDD:278594 | 19/103 (18%) | ||
| SH3_Kalirin_1 | 1643..1707 | CDD:212786 | 7/63 (11%) | ||
| RhoGEF | 1945..2122 | CDD:279015 | |||
| PH2_Kalirin_Trio_p63RhoGEF | 2130..2260 | CDD:270061 | |||
| Net1 | NP_062645.2 | Necessary for nuclear localization | 1..74 | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..42 | ||||
| Nuclear localization signal | 12..19 | ||||
| Nuclear localization signal | 66..72 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 127..151 | 7/23 (30%) | |||
| RhoGEF | 178..354 | CDD:214619 | 48/189 (25%) | ||
| PH_Net1 | 368..502 | CDD:270044 | 22/156 (14%) | ||
| PH | 387..501 | CDD:278594 | 20/136 (15%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 555..595 | 12/70 (17%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R3601 |
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.940 | |||||