Protein Alignment Lip1 and YEH2

DIOPT Version :9

• Sequence 1: NP_001285811.1
• Gene: Lip1 / 43973
• FlyBaseID: FBgn0023496
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_013120.1
• Gene: YEH2 / 850707
• SGDID: S000004010
• Length: 538
• Species: Saccharomyces cerevisiae
• Alignment Length: 476
• Identity: 119/476 - (25%)
• Similarity: 188/476 - (39%)
• Gaps: 126/476 - (26%)

  Fly    39 EEEEEESVE-DETPEDRLQ-------------RKNIK----------------QDSTLSVD-KLI 72
            :.::|.::| |.|...:|.             ..|||                |:..|:.| ||:
Yeast    83 QRDQENNIEYDRTVTSKLSMTSNASLSENGDGNANIKMETNVNQAPYAAENPFQNIALAEDTKLV 147

  Fly    73 -------AKYGYESEVHHVTTEDGYILTMHRIRKQ--------GAPPFLLQHGLVDSSAGFVVMG 122
                   .:||.:.|...|.|:||:|:.:...:.:        ...|.||.|||:.|...|...|
Yeast   148 PDLKYYYKEYGIDIEEFEVETDDGFIIDLWHFKSRLNDGVEEVKREPILLLHGLLQSCGAFASSG 212

  Fly   123 PNVSLAYLLADHNYDVWLGNAR-GNRYSRNHTTLDPDESKFWDFSWHEIGMYDLPAMIDHVLKVT 186
             ..||||.|.:..:||||||.| |.....|...|..|.||.||:..|::..|||.|:|::||..|
Yeast   213 -RKSLAYFLYESGFDVWLGNNRCGLNAKWNMKKLGNDHSKKWDWDMHQMVQYDLKALINYVLDST 276

  Fly   187 GFPKLHYAGHSQGCTSFFV-MCSMRPAYN------DKVVSMQALAPAVY-AKETEDHPYIRAIS- 242
            |:.||....||||.|..|: :.:....|.      ||:.:..||||||| ....::..::|.::
Yeast   277 GYAKLSLVAHSQGTTQGFMGLVNGEKLYASDFKLVDKLENFVALAPAVYPGPLLDEKAFVRLMAK 341

  Fly   243 -----LYFNS-------------LVGSSIREMFNGEFRFLCRMTEETERLCIEAVFGIVGRNWNE 289
                 .||..             :||:.|       |.||       ..:....:|     :||:
Yeast   342 GIDSPWYFGRRSFIPLMMTMRKLMVGTKI-------FSFL-------SYIMFNYLF-----DWND 387

  Fly   290 --FNRKMFPVILGHYPAGVAAKQVKHFIQII------KSGR------------FAPYSYSSNKNM 334
              ::|.:........|..::.|.::.::..:      |.|.            .|.....|..|:
Yeast   388 VLWDRVLRDRNFLFSPVHISVKLMQWWLSPLPNKLSFKKGAEKIFPDKKTWFPIAKNDDDSGNNL 452

  Fly   335 QLYRDHLPPRYNLSLVTVPTFVYYSTNDLLCHPKDVESMCDDL----GNVTGK--YLVPQKEFNH 393
            ...:.||.|:...|.......::....|.|.   |.|.:.:..    .|...|  |:   .|::|
Yeast   453 DNNKLHLNPKRQNSEEFPHIIMFIPKQDRLV---DGERLINHFINHEANAVYKIWYI---DEYSH 511

  Fly   394 MDFLWAIDVRKMLYRRMLQVL 414
            :|.|||.||...:.:.|::.|
Yeast   512 LDVLWAHDVIDRIGKPMIENL 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lip1	NP_001285811.1	Abhydro_lipase	71..122	CDD:282003	17/65 (26%)
		Abhydrolase_1	103..399	CDD:278959	92/349 (26%)
YEH2	NP_013120.1	PLN02872	163..>298	CDD:215470	52/135 (39%)
		Abhydrolase	194..435	CDD:419691	74/260 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341644
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740