Protein Alignment Lip1 and YEH1

DIOPT Version :10

• Sequence 1: NP_523540.1
• Gene: Lip1 / 43973
• FlyBaseID: FBgn0023496
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_013089.1
• Gene: YEH1 / 850648
• SGDID: S000003935
• Length: 573
• Species: Saccharomyces cerevisiae
• Alignment Length: 475
• Identity: 127/475 - (26%)
• Similarity: 197/475 - (41%)
• Gaps: 98/475 - (20%)

  Fly    18 FISRIQGQLIGGEEDEE--------DEEEEEEEEESVEDETP---EDRLQRKNIKQDSTLSVD-- 69
            |::::..:.|..|:..|        :...|....|.|.::.|   ::.||...:.:|.||..|
Yeast   115 FLTKLIFRFIEKEKVTEGVTQGKFNNSSNEIANHEPVFEKIPVQCDNPLQNLILSEDLTLVADLN 179

  Fly    70 KLIAKYGYESEVHHVTTEDGYILTM-HRI--------RKQGAPPFLLQHGLVDSSAGFVVMGPNV 125
            ....:|..:.|...:.||||:::.: |.|        .|:..||.|:.|||:.||..|...| ..
Yeast   180 YYFNQYNIQIEEFRLETEDGFVIDLWHLIPKYRTTDSDKKKRPPILMLHGLLQSSGSFASNG-RK 243

  Fly   126 SLAYLLADHNYDVWLGNAR-GNRYSRNHTTLDPDESKFWDFSWHEIGMYDLPAMIDHVLKVTGFP 189
            ||||.|....||:||||.| |.|...|...: |..:..||:...|:..|||..:||.||..|.|.
Yeast   244 SLAYFLYQSGYDIWLGNNRCGFRPEWNEAKV-PTLASRWDWDLREMVKYDLTLLIDTVLAKTQFE 307

  Fly   190 KLHYAGHSQGCTSFFV------------MCSMRPAYNDKVVSMQALAPAVY-------------- 228
            ||....||||.|..|:            ..|....:..|:.:..|||||||
Yeast   308 KLTLISHSQGTTQGFMGLVNEDKFFPPGSGSKESFFTSKIANYIALAPAVYPGPLLNEKLFVKLM 372

  Fly   229 AKETEDHPYIRAISLYFNSLVGSSIREMFNGE--FRFLCRMTEETERLCIEAVFGIVGRNWNEFN 291
            .||.| :|:....:.:|..::  .:|.:..||  |.|:|           ..:|..: .:||:
Yeast   373 TKEIE-NPWFFGETSFFEIMM--IVRNLCVGESLFSFVC-----------YTIFNYL-FDWND-- 420

  Fly   292 RKMFPVIL--GHY---PAGVAAKQVKHFIQIIKSGRFAPYSYSSNK----NMQLYRD--HLPPRY 345
             .::...|  .|:   |..|:.|.::.::.  .......:.:.|:|    |::.:.|  ..|
Yeast   421 -TLWDTALRDRHFLFSPVHVSVKLMQWWLS--PDPNKVSFKFGSHKMFPDNVKWFSDASKAP--- 479

  Fly   346 NLSLVTVPTFVYYSTNDLLCHPKDVESMCDDLGNVTGK--YLVPQKEFNHMDFLWAIDVRKMLYR 408
            |:.|.............|:.|..:|||      ||..|  |:   .|:.|:|.|||.||.:.:.:
Yeast   480 NIYLFVPKQDRLVDGERLINHFVNVES------NVNYKIWYI---DEYAHIDVLWAHDVIERIGK 535

  Fly   409 RMLQVLGKVPEGSPEEANRS 428
            .:||.|.......|..|..|
Yeast   536 PILQNLNNYYSKKPSSAFES 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lip1	NP_523540.1	PLN02872	70..412	CDD:215470	107/392 (27%)
YEH1	NP_013089.1	PLN02872	169..>326	CDD:215470	59/158 (37%)
		Abhydro_lipase	178..241	CDD:461162	18/62 (29%)